Analysis of the Impact of Clinical Factors on Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Oginski, Natalie; Apel, Hendrik; Richterstetter, Mario; Lieb, Verena; Fiebig, Christian; Goebell, Peter J.; Wullich, Bernd; Sikic, Danijel

doi:10.1159/000520705

Cited by 10 publications

(6 citation statements)

References 37 publications

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“…Another 3 cases had improved erectile function 6 months after the treatment. In addition, the effect was significantly improved for patients with cardiovascular risk factors (p = .026) (Oginski et al, 2022). This study proves that Li-ESWT is an effective but short-term treatment method FIGURE 4 Mechanism of VED for the treatment of ED.…”

Section: Low-intensity Extracorporeal Shock Wave Therapy (Li-eswt)supporting

confidence: 53%

Metabolic Factors in Erectile Dysfunction

Meng,

Rao,

Chen

2024

Frontiers Research Topics

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Frontiers is more than just an open access publisher of scholarly articles: it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed. The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share and generate knowledge. Frontiers provides immediate and permanent online open access to all its publications, but this alone is not enough to realize our grand goals. Frontiers journal seriesThe Frontiers journal series is a multi-tier and interdisciplinary set of openaccess, online journals, promising a paradigm shift from the current review, selection and dissemination processes in academic publishing. All Frontiers journals are driven by researchers for researchers; therefore, they constitute a service to the scholarly community. At the same time, the Frontiers journal series operates on a revolutionary invention, the tiered publishing system, initially addressing specific communities of scholars, and gradually climbing up to broader public understanding, thus serving the interests of the lay society, too. Dedication to qualityEach Frontiers article is a landmark of the highest quality, thanks to genuinely collaborative interactions between authors and review editors, who include some of the world's best academicians. Research must be certified by peers before entering a stream of knowledge that may eventually reach the public -and shape society; therefore, Frontiers only applies the most rigorous and unbiased reviews. Frontiers revolutionizes research publishing by freely delivering the most outstanding research, evaluated with no bias from both the academic and social point of view. By applying the most advanced information technologies, Frontiers is catapulting scholarly publishing into a new generation. What are Frontiers Research Topics?Frontiers Research Topics are very popular trademarks of the Frontiers journals series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area.

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Section: Low-intensity Extracorporeal Shock Wave Therapy (Li-eswt)supporting

confidence: 53%

Metabolic Factors in Erectile Dysfunction

Meng,

Rao,

Chen

2024

Frontiers Research Topics

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“…A recently published study demonstrated an initial good response to ESWT in 50% of patients with ED after 3 months. However, this effect lasted for 6 months in only 16% of patients [28]. On the other hand, a recent systematic review reported that the effect of ESWT for ED decreased at 12-month follow-up, although overall ED improved compared to the pre-treatment situation [20].…”

Section: Discussionmentioning

confidence: 99%

Efficacy and Safety of Extracorporeal Shock Wave Therapy in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Acquired Premature Ejaculation Patients

Sokmen,

Comez

2023

Urol Int

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Introduction: The aim of this study was to evaluate the efficacy and safety of extracorporeal shock wave therapy (ESWT) in patients with acquired premature ejaculation (APE) due to chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Method: Patients with APE due to CP/CPPS between January 2020 and June 2022 were included in the study. Demographic data of the patients were recorded, and the degree of their symptoms was evaluated with the National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI), premature ejaculation diagnostic tool (PEDT), and Premature Ejaculation Profile (PEP). The international prostate symptom index (IPSS) was also used for lower urinary tract symptoms (LUTS), and the international erectile function index-erectile function (IIEF-EF) was used to evaluate erectile functions. All patients received treatment with the Medispec Bold Li-ESWT device without using any anesthesia method (12 sessions). The changes in the symptom scores of the patients were evaluated before the treatment and at the 3rd month after the treatment. Results: A total of 42 patients were included in the study. The mean age of the patients was 43.75 ± 12.03 (20–55), and the mean BMI was 23.58 ± 7.61 (18.03–35.98) kg/m2. The patients’ estimated mean intravaginal ejaculation latency time (IELT) before ESWT was 37.98 ± 21.87 s. After a total of 12 sessions of ESWT, the IIEF-EF, IPSS, NIH-CPSI, and PEP index scores of the patients showed significant improvements (p < 0.001 for each). The IELT mean increased to 74.81 ± 46.79 s (p < 0.001). Posttreatment IELT fold increase was determined as 3.25 ± 1.72 fold. A highly significant positive correlation (p = 0.032; r = 0.839) was found between the CPSI score difference and the posttreatment PEP index score. Conclusion: Li-ESWT treatment is an effective and safe treatment with positive effects on both LUTS and premature ejaculation in patients with APE symptoms due to CP/CPPS. Patients who benefit from CP treatment also have longer IELT times.

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“…Although some progress has been made, further research is needed to explore the effect of various risk factors on Li-ESWT therapy. (20).…”

Section: Discussionmentioning

confidence: 99%

The Efficacy of Low-Intensity Shock Wave Therapy based on the Stratification of Erectile Dysfunction Patients: A Long-term Follow-up

Elshorbagy,

ElSayed,

ElGhoniemy

et al. 2023

Preprint

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Objectives Low intensity extracorporeal shockwave therapy (LIESWT) significantly improves erectile function in patients with vasculogenic erectile dysfunction (ED). We aimed to evaluate the effect of LI-ESWT on different subtypes of ED and to assess through a long-term follow up how long the improvement in erectile function lasts.Methods This was a retrospective review of a prospectively maintained database at the department of urology at Cairo university hospitals. Patients with vasculogenic ED underwent 6–12 sessions of focal LI-ESWT 5000 impulses 0.01 j/mm2 using the electromagnetic Dornier Aries® 1 machine. All patients received at least 6 sessions of LI-ESWT. Then, patients were assessed clinically by using the erection hardness scores (EHS), and erectile function using the international index of erectile function (IIEF-EF) domain score at three months post LI-ESWT and every six months. Also, penile hemodynamics at three months post LI-ESWT and at the last follow up visit.Results 42 patients were identified with mean age 50 ± 12 years, mean ED duration 31 ± 35 months and mean follow up 10 ± 6 months. Overall IIEF-EF was 16 ± 6 and improved to 22 ± 6 at three months and to 21 ± 6 at last follow up (p < 0.01). Minimally important clinical difference was achieved in 69% at three months and in 60% of the whole cohort at last follow up. Risk factors associated with higher MICD at three months were age (p = 0.01), uncontrolled diabetes mellitus ratio (p = 0.04), hypertension (p = 0.24), cardiovascular (p = 0.8), smoker (p = 0.63), and ex-smoker (p = 0.3).Conclusion Li-ESWT have a potential long-term efficacy on different degrees of ED evidenced by the improvement in the penile hemodynamics at the final follow-up particularly in those with controlled diabetes mellitus and advancing age.

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Analysis of the Impact of Clinical Factors on Low-Intensity Extracorporeal Shockwave Therapy for Erectile Dysfunction

Cited by 10 publications

References 37 publications

Metabolic Factors in Erectile Dysfunction

Metabolic Factors in Erectile Dysfunction

Efficacy and Safety of Extracorporeal Shock Wave Therapy in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Acquired Premature Ejaculation Patients

The Efficacy of Low-Intensity Shock Wave Therapy based on the Stratification of Erectile Dysfunction Patients: A Long-term Follow-up

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