The route planning of mapping Unmanned Aerial Vehicles (UAVs) such as image-oriented and tilt photography is not adjusted and optimized in combination with the current situation of acquisition objects, which may cause the risk of collision between UAVs and higher objects. At present, the general design is based on cesium tilt photography 3D model monomer, which does not solve the automatic regular 3D model contour. For the spatial information matching of distribution network equipment, due to the nonlinear coordinate offset adopted by the power grid GIS platform, there is an offset between the collected coordinates and the GIS storage coordinates, which cannot be matched. Therefore, it is very urgent to realize the automatic association between the collected information and the PMS account information. This paper analyzes, designs, and implements the route planning method and the three-dimensional model monomer system. In order to solve the problems of unreasonable route planning of UAV in distribution network grid, collision between UAV and higher objects, incomplete collected data and so on, the route planning method is designed. This method optimizes the route by using the existing three-dimensional data, spatial analysis, and collision detection on the GIS platform. The system is analyzed and verified in a real city.