Analysis of the Interrelationships of Non-Nutrient Blood Flow, Oxygen Delivery, Oxygen Consumption, and the Ratio of Oxygen Delivery/Oxygen Consumption Based on a Mathematical Model of Non-Nutrient Blood Flow

Farrell, Kevin

doi:10.1007/978-1-4684-7790-0_49

Cited by 2 publications

(1 citation statement)

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“…This means that with vasodilation caused by the drug, blood may channel through the capillaries of least resistance. This can result in arteriovenous shunting ( 16,17) through short capillaries and away from the longer "nutritive" capillaries (18,19). Or, steal syndrome (20,21) can result wherein blood is diverted away from capillary beds fed by narrowed or diseased vessels.…”

Section: Microvascular Redistributionmentioning

confidence: 99%

Oxygen Pressure field Theory, The Krogh Cylinder and Long-Term Extra corporeal Perfusion: An Old Concept Provides New Insight

Grist,

Meiling

1993

J Extra Corpor Technol

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This article describes oxygen pressure field theory and its relevance to the application of long-term perfusion support. Prolonged applications of extracorporeal support for cardiac or pulmonary failure require a more perceptive understanding of perfusion and how it works over a period of days or weeks. The key to this understanding lies in the concepts of the Krogh tissue cylinder, the lethal corner and perfused capillary density. The interrelationships of these concepts define the microvascular redistribution system and its need to remain in balance in order to maintain homeostasis. An imbalance in any of the aspects described could result in tissue damage and eventual death. Perfusionists attempting to perform long-term extracorporeal support can improve the odds for patient survival with a clear understanding of oxygen pressure field theory and its associated concepts. By maintaining a balance in the microvascular redistribution system, the perfusionist not only keeps the patient alive, but creates an environment where healing can occur over a period of days or weeks.

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Section: Microvascular Redistributionmentioning

confidence: 99%