Analysis of the most influential publications on vertebral augmentation for treating osteoporotic vertebral compression fracture: A review

Abstract

This study aimed to analyze the most influential publications on vertebral augmentation for treating osteoporotic vertebral compression fracture. The Web of Science database was searched using the key words "percutaneous vertebroplasty," "percutaneous kyphoplasty," "balloon kyphoplasty," "vertebroplasty," "kyphoplasty," and "vertebral augmentation." The top 100 publications were arranged by citations per year and descriptively and visually analyzed. The top 100 publications were cited 25,482 times, with an average of 14.4 citations per paper per year. The corresponding authors of the publications represented 17 nations, with most authors being American (46 authors). Thirty-two journals were involved, with SPINE issuing the most publications (24 papers of the 100). Clinical research (73 of the 100 papers) outnumbered basic studies (14 papers) and systematic reviews (13 papers), and the most publications were published between 2000 and 2004. Co-citation analysis of the key words indicated that the top 5 focus areas were "complication," "balloon kyphoplasty," "vertebral compression fracture," "biomechanics," and "calcium phosphate cement." The top 3 keywords with the strongest citation bursts were "compression fracture," "cement," and "balloon kyphoplasty." The keywords with persistent strong citation bursts are "balloon kyphoplasty" and "augmentation." There are still contrary opinions about vertebral augmentation; new research should be conducted with more deliberate design and longer follow-up.

Porous titanium microsphere kyphoplasty for augmentation treatment of osteoporotic vertebral fractures: Technical report and case series

“…The core purpose of both is to insert bone cement into the fractured vertebral body ( 7 ). The treatment present optimal results only when it was used for “the most suitable patients” ( 8 ). VAPs have shown good uptake, and subsequent studies have shown the effectiveness of vertebroplasty procedures in controlling pain secondary to fracture conversely ( 9 ).…”

Injection of a PMMA‐doped MSC spheroid gel for the treatment of painful osteoporotic vertebral compression fractures

“…Inflammatory cytokines resulting from the fracture also deteriorate the pain 6 . Osteoporotic vertebral compression fractures are a major issue in clinics, 7 as the prevalence rates of these fractures are increasing rapidly and are even highest among multiple types of osteoporotic fractures 8 . In addition, severe pain due to the osteoporotic vertebral compression fractures may increase mortality rates 9 …”

Prognostic factors of balloon kyphoplasty for osteoporotic vertebral fractures with diffuse idiopathic skeletal hyperostosis

“…6 Balloon kyphoplasty (BKP) is a minimally invasive and effective treatment for vertebral fractures, and is widely used for the treatment of OVFs because it provides early pain relief and improves activities of daily living. 7,8 We previously demonstrated that intervertebral bridging osteophyte formation adjacent to the cephalic side of a fractured vertebra, as seen in DISH, is a poor prognostic factor for adjacent vertebral fractures and cement loosening following BKP for OVFs. 9 However, BKP also resulted ABBREVIATIONS BKP = balloon kyphoplasty; DISH = diffuse idiopathic skeletal hyperostosis; ODI = Oswestry Disability Index; OVF = osteoporotic vertebral fracture; PMMA = polymethylmethacrylate; ROC = receiver operating characteristic; VAS = visual analog scale.…”