Analysis of the neurotoxin anisatin in star anise by LC-MS/MS

Mathon, Caroline; Bongard, Benjamin; Duret, M.; Ortelli, Didier; Christen, Philippe; Bieri, Stefan

doi:10.1080/19440049.2013.804955

Cited by 10 publications

(8 citation statements)

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“…Aly et al (2014) mentioned that its fruit is an important traditional Chinese medicine as well as a commonly used spice. Mathon et al (2013) high levels of anisatin in Illicium lanceolatum, I majus, and I anisatum may cause health concerns if they are mididentified or mixed with edible Illicium verum. It is able to increase production of milk new mother (Ibrahim et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Chinese star anise and anise, magic herbs in traditional Chinese medicine and modern pharmaceutical science

Shahrajabian

Sun

Cheng

2019

Asian J. Med. Biol. Res

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Star anise (Illicium verum Hook. f.) is an important herb in traditional Chinese medicine as well as traditional Asian medicine. The fruit is aromatic and has a strong, pungent and mildly sweet taste. Star anise is one of the many species that contain bioactive compounds as well as a number of phenolic and flavonoid compounds, having antioxidant, preservative and antimicrobial properties. All relevant papers in the English language from researchers of different countries were collected. The keywords of Chinese star anise, anise, traditional Chinese medicine and modern pharmaceutical science were searched in Google Scholar, Scopus, Research Gate and PubMed. Its seeds are good source of minerals like calcium, iron, copper, potassium, manganese, zinc, and magnesium. The essential oil of Chinese star anise contains anethole which has shown several functional properties including antimicrobial, antioxidant, hypoglycemic, hypolipidemic and oestrogenic properties. Due to all positive characteristics, such as antidiabetic, hypolipidemic, antioxidant activities, anticancer and antimicrobial properties, both seeds and essential oils of anise is promising for safe use as super food supplements and raw constituents in the both pharmaceutical and food industries. Anise seed oil contains anethol, estragole, eugenol, pseudisoeugenol, methyl chavicol and anisaldehyde, coumarins, scopoleting, umbelliferon, estrols, terpene hydrocarbons, and polyacetylenes as the major compounds. The plant oil has both pharmacological and clinical effects. The pharmacological effects consist of antimicrobial, hepatopreotective, anticonvulsant, anti-inflammatory, antispasmodic, bronchodilator, estrogenic, expectorant and insecticidal effects, and clinical effects such as nausea, constipation, menopausal period, virus, diabetes, obesity and sedative action. Combined with a nutritious diet, other traditional Chinese and Asian medicine, Chinese star anise and ansie seed may improve various aspects of health. More clinical studies are necessary to uncover the numerous substances and their effects in ginseng that contribute to public health. Asian J. Med. Biol. Res. June 2019, 5(3): 162-179

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Section: Introductionmentioning

confidence: 99%

Chinese star anise and anise, magic herbs in traditional Chinese medicine and modern pharmaceutical science

Shahrajabian

Sun

Cheng

2019

Asian J. Med. Biol. Res

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“…3 Assay procedure to evaluate sample preparation methods by measuring sample preparation effect (b/a), matrix factor (c/b), and PE (c/a). Adapted from Mathon et al ( 2013 ) and Noga et al ( 2018 ) …”

Section: Methodsmentioning

confidence: 99%

Impact of sample preparation upon intracellular metabolite measurements in 3D cell culture systems

et al. 2019

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Introduction Interest in cell culture metabolomics has increased greatly in recent years because of its many potential applications and advantages (e.g., in toxicology). The first critical step for exploring the cellular metabolome is sample preparation. For metabolomics studies, an ideal sample preparation would extract a maximum number of metabolites and would enable reproducible, accurate analysis of a large number of samples and replicates. In addition, it would provide consistent results across several studies over a relatively long time frame. Objectives This study was conducted to evaluate the impact of sample preparation strategies on monitoring intracellular metabolite responses, highlighting the potential critical step(s) in order to finally improve the quality of metabolomics studies. Methods The sample preparation strategies were evaluated by calculating the sample preparation effect, matrix factor, and process efficiency (PE) for 16 tobacco exposition-related metabolites, including nicotine, nicotine-derived nitrosamine ketone, their major metabolites, and glutathione, using isotopically-labelled internal standards. Samples were analyzed by liquid chromatography (LC) coupled to high-resolution mass spectrometry (HRMS). Results A sample drying step increased losses or variability for some selected metabolites. By avoiding evaporation, good sample preparation recovery was obtained for these compounds. For some metabolites, the cell or culture type impacted PE and matrix factor. Conclusion In our sample preparation protocol, the drying–reconstitution step was identified as the main cause of metabolite losses or increased data variability during metabolomics analysis by LC-HRMS. Furthermore, PE was affected by the type of matrix. Isotopologue internal standards fully compensate losses or enhancements.

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“…Japanese star anise can be inadvertently ingested because of mistaken identity with Chinese star anise or when adulterated batches of Chinese star anise are used in food preparation. Digestion of false star anise has been associated with serious adverse events such as diarrhea, hallucinations, vomiting, and convulsions 91–93 …”

Section: Safetymentioning

confidence: 99%

Anise

Singletary¹

2022

Nutr Today

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Anise ( Pimpinella anisum L., family Apiaceae) is an aromatic annual herb native to the eastern Mediterranean region and western Asia. Although the small fruit is incorrectly referred to as a seed, nonetheless, the fruit is commonly known as aniseed. When ripe and dried, it is the popular spice. Aniseed and its essential oil are used in traditional therapies, for example, for relief of coughs, respiratory congestion, migraines, gastrointestinal distress, and colic; for treatment of skin infections; as a tranquilizer and aphrodisiac; and to improve lactation. Limited and preliminary clinical research has examined the efficacy of aniseed toward diabetes, dysmenorrhea, and menopausal hot flashes. Antioxidant, anti-inflammatory, and antimicrobial properties also were identified. The present narrative review summarizes human and animal studies reporting potential health benefits of aniseed and highlights areas for future research. Nutr Today 2022;57(2):96-109 A nise ( Pimpinella anisum L., family Apiaceae) is an aromatic annual herb native to the eastern Mediterranean region and western Asia (Figure 1) and cultivated in numerous regions such as southern Europe, northern Africa, South America, China, and Japan. Turkey, Egypt, and Spain are major exporters of this herb, whereas Russia, Spain, and Poland are major suppliers of its oil. The small fruit is incorrectly referred to as a seed. Nonetheless, the fruit is commonly known as aniseed, which when ripe and dried is the popular spice. Aniseed has a sweet, aromatic taste similar to licorice. The fruit and essential oil are used extensively as a flavoring ingredient in numerous foods, including baked goods, sweets, puddings, curries, and frozen dairy desserts, to name a few. The essential oil also is used in perfumes, lotions, soaps, cough preparations, and gum and oral health products. In the food industry, it acts as an antioxidant and preservative. In addition, aniseed is distilled with ethanol to yield distinctive, traditional alcoholic beverages such as anis, Arabian arak, French pastis, Greek ouzo, Russian allasch, Turkish raki, German küstennebel, Italian sambuca, and South American aguardiente. [1][2][3][4] Combining water with these alcoholic beverages in mixed drinks creates a milky cloudiness. This is due to the precipitation of congeners and by-products of distillation that are most soluble in ethanol compared with ethanol and water. In regional foods, this spice is a part of, for example, German springerle or anise-flavored cookies. For these cookies, anise oil (1/ 2 tsp) or extract (1 tsp) can be added directly to the dough, or on the other hand, toasted aniseeds can be distributed on the cookie sheets before baking. Greek butter cookies (koulourakia), traditionally made for Easter and Christmas celebrations, include aniseed (1/2 tsp) and ouzo (1 tbsp) among its flavorings. Likewise, aniseed cookies found in bakeries throughout the Middle East are prepared with ground anise and fennel seeds and savored with a cup of tea or coffee. Preparation of Italian an...

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Analysis of the neurotoxin anisatin in star anise by LC-MS/MS

Cited by 10 publications

References 19 publications

Chinese star anise and anise, magic herbs in traditional Chinese medicine and modern pharmaceutical science

Chinese star anise and anise, magic herbs in traditional Chinese medicine and modern pharmaceutical science

Impact of sample preparation upon intracellular metabolite measurements in 3D cell culture systems

Anise

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