Objective: In this study, it was aimed to retrospectively evaluate the demographic and etiological characteristics, duration of intensive care stay and prognosis of intoxication cases followed up in intensive care unit over a period of 70 months. Materials and Methods: Between January 2011 and October 2016, epidemiology of intoxication cases, who stayed and followed up in Afyon Karahisar University Medical Faculty Hospital Anesthesiology and Reanimation Intensive Care Unit were retrospectively evaluated. Patients were evaluated for age, gender, intoxication effect, cause of intoxication, duration of stay in intensive care unit, need for mechanical ventilation, seasonal variation of intoxication and mortality rates. Results: In the study 122 cases of intoxication were included. Of the patients 81.1% applied with drug or toxic substance intake for attempted suicide. Women made of 65.6% of our patients. The average age of the patients was calculated as 33.12±15.61. When drugs and toxic compounds they took were evaluated, analgesics took the first order, antidepressants took the second order and organophosphates from toxic compounds took the third order. In terms of seasons, the admissions were mostly during spring and winter. The average duration of stay in our intensive care unit was 4.9 days. Mortality rate was determined as 4.9%. Mortalite oranımız %4,9 olarak tespit edilmiştir. Sonuç: Yoğun bakım ünitemizde takip ettiğimiz zehirlenme olgularının büyük bir kısmını kadınların ve gençlerin oluşturduğu tespit edilmiştir. Kolay ulaşılabilen analjezik ve antidepresanlar intihar amaçlı kullanıldığı ve kaza ile en çok organofosfatlara maruz kalındığı sonucuna varılmıştır ve tarımsal ilaç kullanımı hakkında halkın bilinçlendirilmesi ve etiketlerinin açık net ve anlaşılır olması ve gıdalarla aynı ortamda bulundurulmaması zehirlenme vakalarını önemli oranda azaltacağını düşünmekteyiz.