Analysis of the Reasons for the Discontinuation of Orthokeratology Lens Use: A 4-Year Retrospective Study

Ma, Lei; Xu, Minggang; Wang, Jing; Niu, Xiamu

doi:10.1097/icl.0000000000000910

Cited by 8 publications

(3 citation statements)

References 22 publications

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“…In order to prevent and control childhood myopia, orthokeratology (OK) lenses have attracted increasing attention from ophthalmologists and myopic patients because of their good corrective effects and ability to control myopia progression. After more than 30 years of clinical application, the effectiveness of OK lenses in controlling myopia has been confirmed [ 41 ]. Studies have shown that compared to single-vision glasses and contact lenses, the inhibitory effect on axial elongation over 2 years ranges from 32 % to 63 % [ 42 ].…”

Section: Discussionmentioning

confidence: 99%

Effects of orthokeratology on corneal reshaping and the delaying of axial eye growth in children

Zhang,

Zhu,

Zhang

et al. 2024

Heliyon

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Section: Discussionmentioning

confidence: 99%

Effects of orthokeratology on corneal reshaping and the delaying of axial eye growth in children

Zhang,

Zhu,

Zhang

et al. 2024

Heliyon

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“…This dropout rate is consistent with other types of lenses, signifying the comparable discontinuation rates [ 5 , 49 ]. Lina Ma’s extensive 4-year study of 2499 patients reported 50 cases of lens discontinuation, which were attributed to nonadherence (50%), insufficient sleep (18.0%), financial constraints (16.0%), limited effectiveness (10.0%), and corneal infiltrates (6.0%) [ 50 ]. Importantly, there were no significant differences in the causes of discontinuation among the different age groups or genders.…”

Section: Discussionmentioning

confidence: 99%

Systematic Review of Myopia Progression after Cessation of Optical Interventions for Myopia Control

Chiu,

Tsai,

Lee

et al. 2023

JCM

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Despite high discontinuation rates for myopia optical interventions, limited attention has been given to the potential rebound effects post-discontinuation. This systematic review aims to assess the extent of the rebound effects following the cessation of common clinical optical myopia-control interventions in children. A comprehensive search of PubMed, Embase, Cochrane CENTRAL, and ClinicalTrials.gov was conducted from inception to October 2023. The rebound effects, defined as changes in the axial length or spherical equivalent during and after treatment cessation, were categorized into four levels. These studies encompassed 703 participants and spanned from 2019 to 2023, with durations of treatment and cessation ranging from 6 months to 3.5 years and from 2 weeks to 5 years, respectively. This review, encompassing 14 studies, revealed a predominant strong rebound effect in orthokeratology (8 studies), a weak rebound effect in multifocal soft contact lenses (4 studies), and a variable rebound effect in peripheral-plus spectacle lenses (2 studies). Notably, with the increasing cessation duration, the rebound effects diminished, potentially linked to the reversal of choroidal thickening and the disappearance of peripheral myopic defocus. In conclusion, a temporal trend of rebound effects exists in all three myopia optical interventions, possibly contributing to their myopia control mechanisms.

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“…After more than 30 years of clinical use, it has been proven that OK lenses signi cantly reduce myopia [19] . Many patients and their families have agreed that using these lenses for acceptable therapy is acceptable because they may be worn at night and yet provide excellent vision during the day.…”

Section: Discussionmentioning

confidence: 99%

Effect of orthokeratology on the remodeling of the anterior corneal surface and the delaying of eye axis growth in children.

zhang,

zhu,

zhang

et al. 2023

Preprint

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Purpose Our study aims to analyze the effect of orthokeratology (OK) lenses on the development of myopia and eye axis growth in children while also evaluating the corneal reconstruction that occurs as a result. The study seeks to explore the correlation between the flat K of the central cornea and the changes in the axial length resulting from the use of OK lenses. Methods This study focused on patients aged 8–15 years old who were wearing OK lenses and receiving treatment at the pediatric outpatient clinic of the Second Affiliated Hospital of Dalian Medical University. The patients underwent various examinations, including slit lamp examination, visual acuity, computerized optometry, intraocular pressure, biometric measurement, and corneal topography examination before treatment and at 1 month, 3 months, and 6 months after treatment. All patients were divided into four groups according to age: younger group (8–11 years); older group (12–15 years) and initial degree of myopia: (low-grade myopia group (-1.00 D < SE < 3.25D); medium myopia group (-3.25 D < SE < 6.00D). The study followed the inclusion and exclusion criteria. Statistical analysis was conducted using SPSS software, and the expected results were discussed and analyzed. Results After wearing OK lenses, all four groups achieved good visual acuity at the 1-, 3-, and 6-month follow-ups. By the 6th month, both the LL and LM groups, as well as the HL and HM groups, achieved a standard visual acuity of approximately 1.0. There were noticeable differences in the initial eye-axis lengths among the four groups (P < 0.001). Specifically, the LM group had greater eye-axis lengths than the LL group (P < 0.001), while the HM group had greater eye-axis lengths than the HL group (P < 0.001). However, there were no significant differences in the amount of change in the ocular axis at 1, 3, and 6 months between the groups. There was a statistically significant difference in the amount of change in the corneal flat K-value at 1, 3, and 6 months between the groups (P1 = 0.001, P3 = 0.001, and P6 = 0.004, 0.05) but not in the amount of change in the e-value (P1 = 0.205, P3 = 0.252, > 0.05, not statistically significant); regression analysis of the amount of change in the k-value and the amount of change in the e-value revealed no statistically significant differences Conclusion The results show that the shaping effect of OK glasses on the cornea does not correlate significantly with the age and initial myopia of the child and that the rate of delayed axial growth with appropriate OK glasses is consistent across children of different ages and initial myopia; changes in flat K and e values do not accurately predict each individual. Axial growth of the eye may be impacted by changes in e-values due to the shaping action of orthokeratology lenses. According to our theory, axial development may be lessened, and the shift in morphology from the center to the peripheral zone of the cornea will be more obvious with a larger corneal e-value change.

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Analysis of the Reasons for the Discontinuation of Orthokeratology Lens Use: A 4-Year Retrospective Study

Cited by 8 publications

References 22 publications

Effects of orthokeratology on corneal reshaping and the delaying of axial eye growth in children

Effects of orthokeratology on corneal reshaping and the delaying of axial eye growth in children

Systematic Review of Myopia Progression after Cessation of Optical Interventions for Myopia Control

Effect of orthokeratology on the remodeling of the anterior corneal surface and the delaying of eye axis growth in children.

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