Analysis of the Treatment of Diffuse Large B-Cell Lymphoma in Patients with Preexisting Systolic and/or Diastolic Dysfunction at Moffitt Cancer Center

Abstract

Introduction: The treatment of choice for newly diagnosed patients with advanced Diffuse Large B Cell Lymphoma (DLBCL) is R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine And Prednisone). However older patients frequently have concomitant cardiac comorbidities that preclude the use of these agents.