Analysis of Thickness Variation in Biological Tissues Using Microwave Sensors for Health Monitoring Applications

Abstract

The microwave sensing technique is a possible and attractive alternative modality to standard X-rays, magnetic resonance imaging, and computed tomography methods for medical diagnostic applications. This technique is beneficial since it uses non-ionizing radiation and that can be potentially used for the microwave healthcare system. The main purpose of this paper is to present a microwave sensing technique to analyze the variations in biological tissue thickness, considering the effects of physiological and biological properties on microwave signals. In order to fulfill this goal, we have developed a two-port noninvasive sensor system composed of two split ring resonators (SRRs) operating at an Industrial, Scientific, and Medical (ISM) frequency band of 2.45 GHz. The system is verified using the amplitude and phase of the transmitted signal in ex-vivo models, representing different tissue thicknesses. Clinical applications such as the diagnosis of muscular atrophy can be benefitted from this study.

MAS: Standalone Microwave Resonator to Assess Muscle Quality

“…studying the effect of tissue thickness variation [32]. Because these results were promising, we have proposed and are currently developing a tool to assess muscle quality via microwave characterization.…”

“…In 2018, Mohd Shah et al [ 31 ] published a depth assessment study exploring the level to which the electric field penetrates through skin, fat and muscle. A pre-clinical study was performed in laboratory with phantoms (synthetic materials emulating human tissues) and ex vivo porcine tissues studying the effect of tissue thickness variation [ 32 ]. Because these results were promising, we have proposed and are currently developing a tool to assess muscle quality via microwave characterization.…”

A Principal Componet Analysis to detect cancer cell line aggressiveness

“…Biosensors in the microwave field may serve as a complementary or replacement method for early-stage noninvasive prognosis of a variety of illnesses, including malignancies. In this context, the measurement of dielectric properties of biological tissues has achieved significant benefits in biomedical and healthcare due to their high sensitivity, versatility, and reduced invasiveness [6]- [9]. Indeed, this technology has consolidated its use in various fields.…”

Determination of a Measurement Procedure for the Study of Cells’ Dielectric Properties through Descriptive Statistic

“…Over the past two decades, the measurement of dielectric properties has profoundly impacted various scientific fields, including industry, building, heritage materials, and soil pollution assessment [ 1 , 2 , 3 , 4 , 5 , 6 , 7 ]. In recent years, microwave-based sensors have emerged as valuable tools in the biological and biomedical domains, providing non-invasive methods for the early-stage prognosis of diseases, including malignancies [ 8 , 9 , 10 ]. The measurement of the dielectric properties of biological tissues has proven to be highly beneficial in biomedical and healthcare applications due to its high sensitivity, versatility, and non-invasiveness [ 11 , 12 , 13 , 14 ].…”