Analysis of thiol/disulphide homeostasis and oxidant-antioxidant status as a result of exposure to radio-frequency electromagnetic fields

Yavaş, Mehmet Cihan; Yeğin, Korkut; Oruç, Sinem; Delen, Kevser; Sirav, Bahriye

doi:10.1080/15368378.2021.1874970

Cited by 4 publications

(4 citation statements)

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“…Previous studies involving people exposed to mobile phones, experimental animals, and normal and different cancer cell types have reported that EMF may produce signi cant effects through proliferation, apoptosis, DNA damage and oxidative stress, depending particularly on the duration of exposure [3,[16][17][18][19][20][21][22]. Yavas et al reported an increase in total antioxidant, oxidant capacity and oxidative stress index in rats exposed to 2100 MHz RF-EMF [3]. Alkis et al reported increased oxidative DNA damage and lipid peroxidation in the brain tissue of rats exposed to EMF at different frequencies (900, 1800 and 2100 MHz) [1].…”

Section: Discussionmentioning

confidence: 99%

“…The frequencies used by mobile phones range from 800 to 3500 MHz, while those described as 3G operate at a frequency of 2100 MHz. While the use of 4G is becoming more prevalent, the effects of the bandwidth of new generation technologies such as 5G and mobile phones on health are still unknown [1][2][3]. As technology develops, the use of mobile phones becomes more popular, resulting in further discussions on the possible detrimental effects on human health.…”

Section: Introductionmentioning

confidence: 99%

“…It has been emphasized that long-term exposure to EMF leads to changes in biological systems through thermal and non-thermal effects resulting from the transfer of energy to tissue. From a biophysical perspective related to the potential thermal effects, it has been reported that the vibration of electrical charges on the cell membrane surface may lead to impaired electrochemical balance and cell dysfunction due to external oscillation, although studies of this subject to date are controversial [3,4]. Previous studies have reported that the EMF emitted by mobile phones may have adverse effects on the cardiovascular system, immune system, thyroid and hormone secretion, the reproductive system and malignant tumors.…”

Section: Introductionmentioning

confidence: 99%

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Assessing the effect of selenium on cyclin D1 level and nuclear factor kappa b activity in NIH/3T3 fibroblast cells at 2100 MHz electromagnetic field exposure

Ergun,

Ozsobaci,

Yilmaz

et al. 2023

Electromagnetic Biology and Medicine

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Purpose: Although there are various studies on the biological effects of the 2100 MHz electromagnetic eld (EMF), which is among the mobile phone frequencies, there are con icting results in the literature on this subject. Materials andMethods: The present study was designed to assess the effect of 200 nM selenium (Se) on cell viability% [trypan blue], cell cycle biomarker [cyclin D1] and the transcription factor [nuclear factor kappa b (NF-κB)] in NIH/3T3 broblast cells exposed to 2100 MHz mobile phone frequency. Cells were divided to following groups: Control, sham control, 2100 MHz EMF, and 200 nM Se + 2100 MHz EMF for 2 h. And we measurement cell viability%, cyclin D1 level and NF-κB activity. Results and Conclusions: While of cell viability% decreased in 2100 MHz EMF group compared to control group, cell viability% increased in 200 nM Se + 2100 MHz EMF group compared to 2100 MHz EMF. It was also shown that while cyclin D1 level and NF-κB activity increased signi cantly in the 2100 MHz EMF group compared to the control group, the same parameters decreased in the 200 nM Se + 2100 MHz EMF group compared to the 2100 MHz EMF group. Although future studies will be required to investigate the biological effects of EMF emitted by mobile phones, our results provide insight into the molecular mechanisms underlying selenium's protective function and e cacy against 2100 MHz EMF exposure.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Assessing the effect of selenium on cyclin D1 level and nuclear factor kappa b activity in NIH/3T3 fibroblast cells at 2100 MHz electromagnetic field exposure

Ergun,

Ozsobaci,

Yilmaz

et al. 2023

Electromagnetic Biology and Medicine

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“…Sample size calculation: According to previous study (Yavaş et al, 2021), it was observed that standard deviation for TOS value ranged from 1.81 to 2.59. Thus, in this study, standard deviation was considered as 0.11 for BIS value.…”

Section: Methodsmentioning

confidence: 99%

Effects of 3.5‐GHz radiofrequency radiation on energy‐regulatory hormone levels in the blood and adipose tissue

Bektas,

Dasdag,

Altindag

et al. 2024

Bioelectromagnetics

Self Cite

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In recent years exposure of living beings to radiofrequency radiation (RFR) emitted from wireless equipment has increased. In this study, we investigated the effects of 3.5‐GHz RFR on hormones that regulate energy metabolism in the body. Twenty‐eight rats were divided into four groups: healthy sham (n = 7), healthy RFR (n = 7), diabetic sham (n = 7), and diabetic RFR (n = 7). Over a month, each group spent 2 h/day in a Plexiglas carousel. The rats in the experimental group were exposed to RFR, but the sham groups were not. At the end of the experiment, blood and adipose tissues were collected from euthanized rats. Total antioxidant, total oxidant, hydrogen peroxide, ghrelin, nesfatin‐1, and irisin were determined. Insulin expression in pancreatic tissues was examined by immunohistochemical analysis. Whole body specific absorption rate was 37 mW/kg. For the parameters analyzed in blood and fat, the estimated effect size varied within the ranges of 0.215–0.929 and 0.503–0.839, respectively. The blood and adipose nesfatin‐1 (p = 0.002), blood and pancreatic insulin are decreased, (p = 0.001), gherelin (p = 0.020), irisin (p = 0.020), and blood glucose (p = 0.040) are increased in healthy and diabetic rats exposed to RFR. While nesfatin‐1 are negatively correlated with oxidative stress, hyperglycemia and insulin, ghrelin and irisin are positively correlated with oxidative stress and hyperglycemia. Thus, RFR may have deleterious effects on energy metabolism, particularly in the presence of diabetes.

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Assessing the effect of selenium on cyclin D1 level and nuclear factor kappa b activity in NIH/3T3 fibroblast cells at 2100 MHz electromagnetic field exposure

Ergün

Özsobacı

Yilmaz

et al. 2022

Preprint

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Purpose: Although there are various studies on the biological effects of the 2100 MHz electromagnetic field (EMF), which is among the mobile phone frequencies, there are conflicting results in the literature on this subject. Materials and Methods: The present study was designed to assess the effect of 200 nM selenium (Se) on cell viability% [trypan blue], cell cycle biomarker [cyclin D1] and the transcription factor [nuclear factor kappa b (NF-κB)] in NIH/3T3 fibroblast cells exposed to 2100 MHz mobile phone frequency. Cells were divided to following groups: Control, sham control, 2100 MHz EMF, and 200 nM Se + 2100 MHz EMF for 2 h. And we measurement cell viability%, cyclin D1 level and NF-κB activity. Results and Conclusions: While of cell viability% decreased in 2100 MHz EMF group compared to control group, cell viability% increased in 200 nM Se + 2100 MHz EMF group compared to 2100 MHz EMF. It was also shown that while cyclin D1 level and NF-κB activity increased significantly in the 2100 MHz EMF group compared to the control group, the same parameters decreased in the 200 nM Se + 2100 MHz EMF group compared to the 2100 MHz EMF group. Although future studies will be required to investigate the biological effects of EMF emitted by mobile phones, our results provide insight into the molecular mechanisms underlying selenium's protective function and efficacy against 2100 MHz EMF exposure.

show abstract

Analysis of thiol/disulphide homeostasis and oxidant-antioxidant status as a result of exposure to radio-frequency electromagnetic fields

Cited by 4 publications

References 40 publications

Assessing the effect of selenium on cyclin D1 level and nuclear factor kappa b activity in NIH/3T3 fibroblast cells at 2100 MHz electromagnetic field exposure

Assessing the effect of selenium on cyclin D1 level and nuclear factor kappa b activity in NIH/3T3 fibroblast cells at 2100 MHz electromagnetic field exposure

Effects of 3.5‐GHz radiofrequency radiation on energy‐regulatory hormone levels in the blood and adipose tissue

Assessing the effect of selenium on cyclin D1 level and nuclear factor kappa b activity in NIH/3T3 fibroblast cells at 2100 MHz electromagnetic field exposure

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