Analysis of tidal breathing flow volume loop in dogs with tracheal masses

Abstract

TBFVL is a non-invasive technique that is easy to perform and well tolerated by dogs. In the absence of abnormalities detected by routine diagnostic evaluations and arterial blood gas analysis in dogs with intratracheal masses, the TBFVL contributes to the definition of the physiologic status of the airways at the time of testing, and results suggests that these dogs breathe quite normally when they are calm and non-dyspnoeic.

Tidal breathing flow volume loop analysis of 21 healthy, unsedated, young adult maleBeagle dogs

“…Despite the fact that TBFVL analysis has been used in veterinary medicine since 1986, there are no studies that have aimed specifically to develop a database of reference values for healthy dogs . In an attempt to bypass this problem, all existing reports use their own normal reference population . The present study aimed to take a fundamental step in the development of a database.…”

“…This can be observed in both phases of respiration . However, it has been reported that such changes are not always detected in dogs with airway obstruction, probably because the flow depends on multiple factors such as V T , time, pressure, effort and resistance . Additionally, diseases that can influence intrathoracic pressure during both respiratory phases may cause the flow‐related inspiratory and expiratory parameters to have values within the reference ranges .…”

“…During the procedure, the software displayed flow–volume loops and flow versus time curves. The system was calibrated before each measurement with a standard volume syringe (model 1000 CalSTAT, Volume Calibration Standard, Electronics Inc., Med Science, St Louis, MO, USA) by the injection of a known volume of air through the system and the integration of the flow with that volume . For each dog, TBFVL measurements were recorded for approximately 10 min and data from 10 representative breaths were obtained.…”

“…In veterinary medicine, the evaluation of the tidal breathing flow volume loop (TBFVL) was initially proposed for the clinical assessment of airway obstruction in conscious dogs . Since then, various studies have been conducted and reported in the veterinary literature on the use of TBFVL for the diagnosis and/or management of canine upper or lower respiratory diseases …”

Respiratory dysfunction in unsedated dogs with golden retriever muscular dystrophy

“…Tidal breathing flow-volume loops in upper airway obstruction of infants[56,57]and dogs[33-36,58] show characteristic flattening of the inspiratory limb. Although the shape of the flow-volume loops from GRMD dogs was consistent with upper airway obstruction, the expiration limb was consistently abnormal rather than the inspiratory limb, when compared with the control dog population.…”