Analysis of urine by MIP-OES: challenges and strategies to correct matrix effects

Abstract

This work investigated the performance of microwave induced plasma optical emission spectrometry (MIP-OES) for urine analysis, a complex matrix containing carbon and high concentration of easily ionizable elements (EIEs). The...

Atomic spectrometry update: review of advances in the analysis of clinical and biological materials, foods and beverages

“…Matrix effect is one of the main problems affecting the determination of trace elements . The work of Fontoura et al 126 investigated the effect of a complex matrix, such as urine, on the optical emission signals of 14 elements (Al, As, Ba, Be, Bi, Ca, Cd, Co, Cr, Cu, Li, Mg, Pb and Sb). Since these effects may involve enhancement or depression of the signals, as well as being absent at all, depending on the analyte, the authors studied the plasma operational conditions for MIP-OES, as well as external calibration vs. internal standardisation, and three levels of dilution (2-, 20-, and 200-fold).…”

The Saha ionisation equilibrium shift correction model applied to MPT-OES for analysing complex matrix samples: an example for brine samples

“…1 It is worth noting that microwave induced plasma (MIP) is more susceptible to this interference than inductively coupled plasma (ICP), as reported in previous studies. [2][3][4] Recently, several high-power MIPs have been reported to exhibit similar trends when subjected to matrix interference of easily ionisable elements (EIEs). Specically, matrices Na and Ca have a promoting effect on most atomic lines, while nearly all ionic lines show an inhibitory effect.…”

“…10,11 Furthermore, some atomic and ionic lines with similar energies showed similar trends with increasing matrix concentration (0-1% w/w), suggesting that the ion-atom equilibrium might remain unchanged. 10 In addition to traditional calibration strategies for OES such as internal standardisation calibration (IS), 3,4,[12][13][14][15] external standard calibration (ES) 13,14,16 and standard addition (SA), 13,15 several novel strategies have been proposed to correct for non-spectral interferences. These strategies can be broadly categorized as follows.…”

“…1 It is worth noting that microwave induced plasma (MIP) is more susceptible to this interference than inductively coupled plasma (ICP), as reported in previous studies. 2–4…”

Automated standard dilution analysis using a four-port switching valve for fast inductively coupled plasma optical emission spectrometry determination

“…In addition, nding a suitable IS species can be difficult for many applications. 3,7,8,10 Matrix effects are related to measurement interferences caused by concomitant species in the sample. 3 When such effects are signicant, neither EC nor IS can successfully provide accurate results.…”