Analysis of vessel wall morphology, blood flow velocity, and the hemostatic system in a patient with a large intracoronary thrombus

Haude, Michael; Altmann, Christoph; Eick, Beate; Liu, Fengqi; Schwippert, B.; Tschöpe, D; Erbel, Raimund

doi:10.1002/(sici)1097-0304(199803)43:3<298::aid-ccd12>3.0.co;2-i

Cited by 5 publications

(2 citation statements)

References 45 publications

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“…20,21 It has also been reported that administration of the platelet GP IIb/IIIa receptor antagonist was effective for a patient with AMI caused by a large thrombus. 22 We therefore suggest that the treatment of the intracoronary thrombus, especially a large thrombus, is important during primary PTCA.…”

Section: Discussionmentioning

confidence: 99%

Relation Between Coronary Thrombus and Angiographic No-Flow During Primary Angioplasty in Patients With Acute Myocardial Infarction

et al. 1999

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ecent angiographic, angioscopic and pathologic study demonstrate that an intracoronary thrombus is frequently observed and related in the clinical setting of acute myocardial infarction (AMI). 1,2 Primary angioplasty for AMI is a mechanical and direct approach for coronary stenosis or occlusion, and for intracoronary thrombus, and has been reported as a superior revascularization technique over systemic thrombolysis. 3,4 However, several limitations still remain, including a high reocclusion rate and slow flow or no reflow after revascularization. 5-7 A direct approach to the thrombus with a balloon inflation technique may produce thrombus fragmentation, and consequently trigger distal embolization leading to no flow. In the present study, we retrospectively studied the relation of angiographic no-flow to the intracoronary thrombus in the infarct-related artery during primary percutaneous transluminal coronary angioplasty (PTCA) for AMI Methods Study PopulationAmong the patients who were admitted to Kumamoto

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Section: Discussionmentioning

confidence: 99%

Relation Between Coronary Thrombus and Angiographic No-Flow During Primary Angioplasty in Patients With Acute Myocardial Infarction

et al. 1999

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“…The intravascular ultrasound (IVUS) was not systematically implemented as it should be due to the retrospective nature of the current study. It was carried out in just 6 patients in the literature and shows an absence of atherosclerosis in two cases (44,45) in addition to inconspicuous signs of atherosclerosis in the other cases (46,47). Thus, prospective studies on the pathophysiological mechanisms using new technologies such as intravascular ultrasound (48) would allow better analysis of the vessel structure.…”

Section: Limitations Of the Studymentioning

confidence: 99%

Myocardial Infarction and Normal Coronary Arteries: The Experience of the Cardiology Department of Sfax, Tunisia

et al. 2012

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Objective The purpose of the present study is to describe our experience with patients who have a transmural myocardial infarction (MI) in the presence of a normal coronary artery. The clinical profile, demographic characteristics and outcomes of these patients are discussed. Methods Between January 2006 and August 2011, 21 patients who presented with a Q-wave myocardial infarction were found to have normal coronary arteries. The prevalence rate of this entity was 1.5% (21 out of 1,400 Q wave MI patients). These patients were characterized by their young age (the mean age=44.95± 14.86), male dominance (90.47%), and a high prevalence of smoking (85.71%). In this study, 4 patients have an evident spontaneous spasm shown on coronary angiography which disappeared after intracoronary injection of nitrates. Coagulation Disorders, such as activated protein C resistance (APC) resistance, protein C deficiency and antiphospholipid antibody syndrome were found in 4 of 12 patients who underwent systematic examination. One patient had a history of lung cancer which may be associated with a hypercoagulable state and may explain the occurrence of myocardial infarction with a normal coronary artery. The mean left ventricle ejection was 56. 5±12. The mean follow-up was 24±10 months. Six patients developed residual chest pain which was generally easily controlled by anti-spastic therapy and no patient had a major cardiovascular event.Conclusion Patients with Q-wave MI and with normal coronary arteries seem to have a good short and long-term prognosis especially when they are treated with an exclusive medical strategy.

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Extraction of large intracoronary thrombus in acute myocardial infarction by percutaneous fogarty maneuver: Intentional abuse of a novel interventional device

Eggebrecht

Baumgart

Naber

et al. 2002

Cathet Cardio Intervent

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Intracoronary thrombus in the infarct-related artery remains a challenge for interventional catheter-based techniques in acute myocardial infarction and may result in severe complications due to distal embolization. We describe a patient with acute myocardial infarction in whom a large intracoronary thrombus of the left anterior descending coronary artery was successfully removed by percutaneous Fogarty maneuver using an expanded filter protection device.

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Analysis of vessel wall morphology, blood flow velocity, and the hemostatic system in a patient with a large intracoronary thrombus

Cited by 5 publications

References 45 publications

Relation Between Coronary Thrombus and Angiographic No-Flow During Primary Angioplasty in Patients With Acute Myocardial Infarction

Relation Between Coronary Thrombus and Angiographic No-Flow During Primary Angioplasty in Patients With Acute Myocardial Infarction

Myocardial Infarction and Normal Coronary Arteries: The Experience of the Cardiology Department of Sfax, Tunisia

Extraction of large intracoronary thrombus in acute myocardial infarction by percutaneous fogarty maneuver: Intentional abuse of a novel interventional device

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