Analysis of Y-chromosomal SNP haplogroups and STR haplotypes in an Algerian population sample

Robino, Carlo; Crobu, Francesca; Gaetano, Cornelia Di; Bekada, Asmahan; Benhamamouch, Soraya; Cerutti, N.; Piazza, Alberto; Inturri, S.; Torre, Carlo

doi:10.1007/s00414-007-0203-5

Cited by 64 publications

(43 citation statements)

References 27 publications

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“…25 Interestingly, chromosomes of haplogroup R-P25/R-M173, ancestral for M269 as well as for other 'Eurasian' downstream markers, have been found to be present in northern Africa (1% in Algeria, 4% in Tunisia, and 2-4% in Egypt). 20,23,26 The presence of R-P25 Y chromosomes has also been reported in population groups from the Sudan; 27 however, as no internal markers were typed, the sub-haplogroup affiliation of these chromosomes remains undefined.…”

Section: Introductionmentioning

confidence: 93%

Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages

et al. 2010

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Although human Y chromosomes belonging to haplogroup R1b are quite rare in Africa, being found mainly in Asia and Europe, a group of chromosomes within the paragroup R-P25* are found concentrated in the central-western part of the African continent, where they can be detected at frequencies as high as 95%. Phylogenetic evidence and coalescence time estimates suggest that R-P25* chromosomes (or their phylogenetic ancestor) may have been carried to Africa by an Asia-to-Africa back migration in prehistoric times. Here, we describe six new mutations that define the relationships among the African R-P25* Y chromosomes and between these African chromosomes and earlier reported R-P25 Eurasian sub-lineages. The incorporation of these new mutations into a phylogeny of the R1b haplogroup led to the identification of a new clade (R1b1a or R-V88) encompassing all the African R-P25* and about half of the few European/west Asian R-P25* chromosomes. A worldwide phylogeographic analysis of the R1b haplogroup provided strong support to the Asia-to-Africa back-migration hypothesis. The analysis of the distribution of the R-V88 haplogroup in 41800 males from 69 African populations revealed a striking genetic contiguity between the Chadic-speaking peoples from the central Sahel and several other Afroasiatic-speaking groups from North Africa. The R-V88 coalescence time was estimated at 9200-5600 kya, in the early mid Holocene. We suggest that R-V88 is a paternal genetic record of the proposed mid-Holocene migration of proto-Chadic Afroasiatic speakers through the Central Sahara into the Lake Chad Basin, and geomorphological evidence is consistent with this view.

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Section: Introductionmentioning

confidence: 93%

Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages

et al. 2010

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“…The distribution of E3b1b-M81 chromosomes in Africa closely matches the areas of distribution of Berber speaking populations, suggesting close Hg-ethnicity specificity. Interestingly, haplotype 13-14-30-24-9-11-13, associated to the E3b1b-M81 chromosomes, 23,36 is also present in Sicily. On the basis of the YHRD database, this haplotype occurs with high frequency in the Berber population of Tunisia, whereas it is less common elsewhere in North Africa.…”

Section: Discussionmentioning

confidence: 98%

Differential Greek and northern African migrations to Sicily are supported by genetic evidence from the Y chromosome

et al. 2008

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“…15,16 Notably, it also occurs at informative 45% frequencies in Northeast Italy and the Balkans, 17 Turkey, 7 Iran, 8 the Caucasus (this study), Iraq and Lebanon, 18 Pakistan 10 and Algeria. 19 Haplogroup R1b frequency in Europe is clinal with increasing frequencies observed in Northwest Europe, a pattern that has been ascribed to the persistance of Palaeolithic Y chromosomes in Europe after a Neolithic demic diffusion from the Near East. 20,21 Interestingly, attempts to date the Y-STR-based diversity of R1b-M269 chromosomes in populations from Europe and Turkey have yielded Holocene expansion times in both regions.…”

Section: Introductionmentioning

confidence: 91%

A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe

Myres¹,

et al. 2010

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The phylogenetic relationships of numerous branches within the core Y-chromosome haplogroup R-M207 support a West Asian origin of haplogroup R1b, its initial differentiation there followed by a rapid spread of one of its sub-clades carrying the M269 mutation to Europe. Here, we present phylogeographically resolved data for 2043 M269-derived Y-chromosomes from 118 West Asian and European populations assessed for the M412 SNP that largely separates the majority of Central and West European R1b lineages from those observed in Eastern Europe, the Circum-Uralic region, the Near East, the Caucasus and Pakistan. Within the M412 dichotomy, the major S116 sub-clade shows a frequency peak in the upper Danube basin and Paris area with declining frequency toward Italy, Iberia, Southern France and British Isles. Although this frequency pattern closely approximates the spread of the Linearbandkeramik (LBK), Neolithic culture, an advent leading to a number of pre-historic cultural developments during the past r10 thousand years, more complex pre-Neolithic scenarios remain possible for the L23(xM412) components in Southeast Europe and elsewhere.

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Analysis of Y-chromosomal SNP haplogroups and STR haplotypes in an Algerian population sample

Cited by 64 publications

References 27 publications

Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages

Human Y chromosome haplogroup R-V88: a paternal genetic record of early mid Holocene trans-Saharan connections and the spread of Chadic languages

Differential Greek and northern African migrations to Sicily are supported by genetic evidence from the Y chromosome

A major Y-chromosome haplogroup R1b Holocene era founder effect in Central and Western Europe

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