Analysis of Y chromosome STR haplotypes in the European part of Russia reveals high diversities but non-significant genetic distances between populations

Roewer, Lutz; Willuweit, Sascha; Krüger, Carmen; Nagy, Marion; Rychkov, S. Yu.; Morozowa, Irina; Naumova, O. Yu.; Schneider, Yuriy; Жукова, О. В.; Stoneking, Mark; Nasidze, Ivan

doi:10.1007/s00414-007-0222-2

Cited by 56 publications

(20 citation statements)

References 22 publications

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“…In contrast, the deepest divergence between the European populations included in [23] is Φ ST ≈0.08 (minimal haplotype data), and several studies including U.S. populations have described significant differences mainly between different ethnic groups (e.g., European and African Americans; [3,12,20]. Nonsignificant differentiation is recently also reported between geographically relatively widely separated populations in Russia [21]. From the forensic point of view, the substructure effects in Finland are exacerbated by the fact that clearly distinct Y-STR haplotypes dominate in different subpopulations (Fig.…”

Section: Population Subdivisionmentioning

confidence: 82%

The effect of number of loci on geographical structuring and forensic applicability of Y-STR data in Finland

et al. 2008

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The Y-chromosomal diversity among Finnish males is characterized by low diversity and substantial geographical substructuring. In a 12-locus data set (PowerPlexY), especially the eastern parts of the country showed low levels of variation, and the western, middle, and eastern parts of Finland differed from each other by their Y-short tandem repeat (STR) haplotype frequencies (Palo et al., Forensic Sci Int Genet 1:120-124, 2007). In this paper, we have analyzed geographical patterns of Y-STR diversity using both 12-locus (PowerPlexY) and 17-locus (Yfiler) data sets from the same set of geographically structured samples. In the larger data set, the haplotype diversity is significantly higher, as expected. The geographical distribution of haplotypes is similar in both data sets, but the level of interregional differences is significantly lower in the Yfiler data. The implications of these observations on the forensic casework are discussed.

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Section: Population Subdivisionmentioning

confidence: 82%

The effect of number of loci on geographical structuring and forensic applicability of Y-STR data in Finland

et al. 2008

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“…The order of loci given above has been used in the following text to report haplotypes in the form of a text string where alleles of consecutive Y-STR loci are separated by hyphens. The population samples typed for 12 loci were as follows: Poles from southern Poland (N 5 228; designated SPO, ; Russians from the European part of Russiaone sample (N 5 545) designated as RUR (Roewer et al, 2008) and the other (N 5 405) designated as RUS. The latter Russian population sample has been partially published by us (Derenko et al, , 2007, but the complete set of Y-STR profiles is included here, in Supporting Information Table 1.…”

Section: Data Used For Comparison Purposesmentioning

confidence: 99%

Similarities and distinctions in Y chromosome gene pool of Western Slavs

Woźniak

Malyarchuk

Derenko

et al. 2010

American J Phys Anthropol

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Analysis of Y chromosome Y-STRs has proven to be a useful tool in the field of population genetics, especially in the case of closely related populations. We collected DNA samples from 169 males of Czech origin, 80 males of Slovakian origin, and 142 males dwelling Northern Poland. We performed Y-STR analysis of 12 loci in the samples collected (PowerPlex Y system from Promega) and compared the Y chromosome haplotype frequencies between the populations investigated. Also, we used Y-STR data available from the literature for comparison purposes. We observed significant differences between Y chromosome pools of Czechs and Slovaks compared to other Slavic and European populations. At the same time we were able to point to a specific group of Y-STR haplotypes belonging to an R1a haplogroup that seems to be shared by Slavic populations dwelling in Central Europe. The observed Y chromosome diversity may be explained by taking into consideration archeological and historical data regarding early Slav migrations.

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“…The Y chromosome is more sensitive to genetic drift due to its fourfold smaller effective population size compared with an autosome. Therefore, it is necessary to verify that no population substructure exists before pooling Y-STR data from different regions of the country [1,2]. Although studies have been undertaken to establish the Korean Y-STR databases [3][4][5], a focus on population substructure of Y-STR haplotypes within Korea has not yet drawn much attention.…”

Section: Introductionmentioning

confidence: 99%

Y chromosome homogeneity in the Korean population

et al. 2010

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The distribution of Y-chromosomal variation from the 12 Y-SNP and 17 Y-STR markers was determined in six major provinces (Seoul-Gyeonggi, Gangwon, Chungcheong, Jeolla, Gyeongsang, and Jeju) to evaluate these populations' possible genetic structure and differentiation in Korea. As part of the present study, a 10-plex SNaPshot assay and two singleplex SNaPshot assays were developed. Based on the result of 12 Y-SNP markers (M9, M45, M89, M119, M122, M174, M175, M214, RPS4Y, P31, SRY465, and 47z), almost 78.9% of tested samples belonged to haplogroup O-M175 (including its subhaplogroups O3-M122: 44.3%, O2b*-SRY465: 22.5%, O2b1-47z: 8.7%), and 12.6% of the tested samples belonged to haplogroup C-RPS4Y. A total of 475 haplotypes were identified using 17 Y-STR markers included in the Yfiler kit, among which 452 (95.2%) were individual-specific. The overall haplotype diversity for the 17 Y-STR loci was 0.9997 and the discrimination capacity was 0.9387. Pairwise genetic distances and AMOVA of the studied Korean provinces reflected no patrilineal substructure in Korea, except for Jeju Island. Thus, this survey shows that the present data of Korean individuals could be helpful to establish a comprehensive forensic reference database for frequency estimation.

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Analysis of Y chromosome STR haplotypes in the European part of Russia reveals high diversities but non-significant genetic distances between populations

Cited by 56 publications

References 22 publications

The effect of number of loci on geographical structuring and forensic applicability of Y-STR data in Finland

The effect of number of loci on geographical structuring and forensic applicability of Y-STR data in Finland

Similarities and distinctions in Y chromosome gene pool of Western Slavs

Y chromosome homogeneity in the Korean population

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