We compute the full three-loop coefficient functions for the structure functions F 2 and F L in massless perturbative QCD. The results for F L complete the next-to-next-to-leading order description of unpolarized electromagnetic deep-inelastic scattering. The third-order coefficient functions for F 2 form, at not too small values of the Bjorken variable x, the dominant part of the next-to-next-tonext-to-leading order corrections, thus facilitating improved determinations of the strong coupling α s from scaling violations. The three-loop corrections to F L are larger than those for F 2 . Especially for the latter quantity the expansion in powers of α s is very stable, for photon virtualities Q 2 ≫ 1 GeV 2 , over the full x-range accessible to fixed-target and collider measurements.