We prove the existence of global solutions to the Cauchy problem of the Hartree equationiut + ∆u + (| · | −γ * |u| 2 )u = 0, u|t=0 = φ, 0 < γ < min(2, n) for large data φ in L p -spaces when p < 2 is sufficiently close to 2. Moreover, the global solution satisfiesThe solution is established using a data-decomposition argument, the idea of YI.Zhou's work and a uniqueness assertion via generalized Strichartz type estimates.