Analytical Anisotropic Algorithm Calculation in Total Body Irradiation: A Comparison with Monte Carlo Calculation and Dosimetry

Saikkonen, Aleksi; Ojala, Jarkko; Keyriläinen, Jani

doi:10.26502/jcsct.5079136

Cited by 2 publications

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“…From the HI and CI obtained in the current study, we can conclude that both the TPSs had the potential to create clinically deliverable plans with a good sparing of OARs. Our results was similar to those reported by Lu W., Adrian N., and Aleksi [11,[13][14][15]. Planning and dose calculation time was 4 and 5).…”

Section: Discussionsupporting

confidence: 91%

Comparison of Different Dosimetric Indices for Volumetric Arc Modulated Treatment Planning Using 2 Different Treatment Planning Systems: A Feasibility Study for Total Body Irradiation

Kumari,

Yadav,

Kumar

2023

Asian Pac J Cancer Care

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Objective: To compare two different treatment planning systems (TPSs) for plan quality and to check the feasibility of VMAT TBI on the Elekta linear accelerator ‘Versa HD’. Methods: Ten clinical VMAT TBI plans were replanned in Monaco TPS version 5 for retrospective dosimetric analysis and to check the feasibility of treatment delivery in Elekta Versa HD. A dose of 12 Gy in 6 fractions was prescribed to cover 95% PTV. The OARs were the lungs, kidneys, heart, liver, and brain. Dosimetric optimization and calculation were performed in Monaco TPS with a statistical uncertainty of 1%, 2 mm grid. The chosen criterion for plan evaluation and comparison was based on plan quality, dosimetric indices like conformity and homogeneity index, and OAR doses. The comparison of time for optimization, monitor units, and beam on time was also analyzed. Pre-treatment verification using Octavious phantom and gamma analysis using Low’s method with a dose difference of 3% and distance to agreement 3mm criteria was done. The dosimetry of 2 VMAT TBI plans were compared using Wilcoxon signed rank test. Result: The calculated average maximum and mean doses of the PTV were 14.3321Gy and 12.235Gy for eclipse; and 14.428Gy and 12.198Gy for the Monaco system, respectively. The planning time in Monaco was approx. 4.5–6hrs compared to 14–18hrs for Eclipse TPS. Statistically significant difference was observed between the results of 2 TPSs in terms of monitor units, mean doses to lungs, kidneys, heart, and liver and planning time (P < 0.05). However, calculated p values for HI, CI, and brain for both VMAT TBI plans were not statistically different. Conclusion: The study showed the feasibility of VMAT TBI for VERSA HD as it offers faster, better optimization in a single target compared to the Eclipse.

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Section: Discussionsupporting

confidence: 91%

Comparison of Different Dosimetric Indices for Volumetric Arc Modulated Treatment Planning Using 2 Different Treatment Planning Systems: A Feasibility Study for Total Body Irradiation

Kumari,

Yadav,

Kumar

2023

Asian Pac J Cancer Care

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Validation of HDR brachytherapy doses in the treatment of keloid scars using the egs_brachy Monte Carlo application

et al. 2023

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Objective: Radiotherapy is a well-known alternative in the treatment of keloid scars to reduce the recurrence of scars. The purpose of this study was to investigate the feasibility and accuracy of dose delivered from a high-dose-rate (HDR) afterloaders in keloid scar brachytherapy using Monte Carlo (MC) simulations and measurements. Approach: Treatment doses and central axis (CAX) dose profiles were measured using radiophotoluminescence dosimeters and radiochromic films, respectively, with two HDR afterloaders, both using an Ir-192 source, in a phantom made of solid water and polycarbonate sheets. The nominal treatment dose calculated by the AAPM Task Group No. 43 (TG-43) dose model was set to 8.5 Gy at a distance of 0.5 cm laterally from the middle of the source line located in a plastic applicator simulating a 15 cm long surgically removed scar treatment with 30 equally spaced (0.5 cm) source positions. The dose profiles were measured at three different distances from the applicator and the absolute doses at four points at different distances. MC simulations were performed using the egs_brachy, which is based on EGSnrc code system. Main results: The measured and simulated dose profiles match well, especially at 10.0 mm (difference < 1 %) and 15.0 mm depths (difference < 4 %), and with a small dose difference at 5.0 mm depth (difference < 4 %). Point dose measurements agreed well in the dose maximum area (difference < 7 %) with the simulated dose profiles, although the largest difference near the edge of the profile was < 30 %. The dose differences between the TG-43 dose model and the MC simulation were small (differences < 4 %). Significance: Simulated and measured dose levels at a depth of 0.5 cm showed that the nominal treatment dose can be achieved with the utilized setup. The measurement results of the absolute dose agree well with the corresponding simulation results.

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Analytical Anisotropic Algorithm Calculation in Total Body Irradiation: A Comparison with Monte Carlo Calculation and Dosimetry

Cited by 2 publications

References 0 publications

Comparison of Different Dosimetric Indices for Volumetric Arc Modulated Treatment Planning Using 2 Different Treatment Planning Systems: A Feasibility Study for Total Body Irradiation

Comparison of Different Dosimetric Indices for Volumetric Arc Modulated Treatment Planning Using 2 Different Treatment Planning Systems: A Feasibility Study for Total Body Irradiation

Validation of HDR brachytherapy doses in the treatment of keloid scars using the egs_brachy Monte Carlo application

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