Analytical capabilities of inductively coupled plasma orthogonal acceleration time-of-flight mass spectrometry (ICP-oa-TOF-MS) for multi-element analysis of food and beverages

Advanced Mass Spectrometry

“…A reflectron TOF analyzer is placed orthogonally to the quadrupole and serves as a mass resolving device for both MS and MS/MS modes [48][49][50][51][52][53][54][55]. A collision cell is located between the quadrupole and the TOF analyzer to induce fragmentation in MS/MS experiments [56][57][58][59][60][61]. The QqTOF is almost as used as TOF mass analyzers ( Table 2).…”

“…ICP-TOF Multielement analysis of food and beverages [57] QqTOF Ni speciation in tea infusions [62] ICP-TOF Arsenic species in methanolic extracts of cod liver [63] ICP-MS Analysis of heavy metal content in Indocalamus tessellatus samples [56] LC-TOF Simultaneous determination of B complex vitamins in nutritional yeast [64] MALDI-TOF Monitoring of barley starch amylolysis [65] LC-TOF Determination of free and bound phenolic compounds in buckwheat spaghetti. Effect of thermal processing [66] LC-TOF Analysis of pesticides in fruits and vegetables [67] GC-TOF Quantitative analysis of acetaldehyde in foods consumed [68] LC-TOF Screening natural antioxidants in peanut shell [69] UHPLC-TOF Hexabromocyclododecane diastereomers [70] Type Application References UHPLC-TOF 19 antibiotics in dairy products [71] MALDI-TOF Microscale strategy to detect spermine and spermidine in food [72] LC-TOF Determination of phthalates in edible salts from food markets in Korea [73] LC-QqTOF Simultaneous determination five major antioxidant compounds [74] MALDI-TOF Monitoring of she-donkey's milk contamination or adulteration [75] MALDI-TOF Quantitating curcumin in food condiments and dietary supplements and screening of acrylamide-induced ROS protein indicators [76] LC-QqTOF Quantitating curcumin in food condiments and dietary supplements and screening of acrylamide-induced ROS protein indicators [45] UHPLC-TOF Analysis of illicit dietary supplements sold in the Italian market: Identification of a sildenafil thioderivative as adulterant [46] LC-TOF Simultaneous investigation of sesquiterpenes, pyrrolizidine alkaloids, and N-oxides in butterbur (Petasites hybridus) [77] UHPLC-QqTOF Determination of 141 pesticides in tea [78] UHPLC-QqTOF Determination of tadalafil and N-desmethylsibutramine in health and dietary supplements [79] LC-QqTOF Seven fluorescent whitening agents in food contact paper package materials [80] Lipidomics GC × GC-TOF Unsaponifiable fraction of lipids belonging to various types of milk [22] UHPLC-QqTOF Rapid and highly accurate detection of steryl glycoside [81] MALDI-TOF Rapid lipid profiling of bacteria [82] MALDI-TOF Detection of glycated phosph...…”

“…It seems that just these advantages open new opportunities for ICP-MS analysis also in the field of food analysis because of the growing trend toward increasing consumer awareness [57].…”

“…A number of label-free quantitative studies have successfully applied MS E , including identification of differentially expressed proteins in rat frontal cortex following subchronic treatment with haloperidol or olanzapine, profiling the serum [54] and postmortem brain tissues of schizophrenia patients [53], and analyzing the human pituitary proteome [55]. MS E has also been employed in the studies of the proteins from plants [56,57] and microorganisms [40,48,58,59]. Figure 10 shows the MS E analysis of flavonoids.…”

Screening and confirmatory methods for the detection of heavy metals in foods

“…To overcome this drawback, improvement in this instrumentation may be a possible resolution, for example using magnetic sector high resolution spectrometer. 89 The last point relates to the sample treatment. In our opinion, in order to avoid environmental contamination and to have a complete digestion of complex matrices such as milk, microwave assisted digestion is highly recommended.…”