Analytical Design and Operation of Systems with Crystallization, Filtration, and Recycling

Abstract

Previously, Ward et al. [Ward, J. D.; Doherty, M. F.; Yu, C. C. Plantwide Operation and Control of Processes with Crystallization. AIChE J. 2007AIChE J. , 53, 2885AIChE J. -2896 published a novel shortcut method for predicting how process operation will be affected by the choice of control structure for a plant with reaction, crystallization, and recycling. The analysis assumed the presence of a continuous filter but did not model its operation. In this article, we introduce an analogous dimensionless model for a continuous rotary drum filter and show that a similar methodology can be used to predict the behavior of a combined crystallizer and filter, and a reactor, crystallizer, filter, and recycle circuit. We show the effect of the crystallizer operating policy on the operation of the filter and show that the overall operation of the combined plant can be predicted for a given choice of controlled variables. This facilitates the screening of control structures by rapid elimination of control structures that are likely to lead to infeasible or uneconomic modes of operation.

Implementation and Application of Image Analysis-Based Turbidity Direct Nucleation Control for Rapid Agrochemical Crystallization Process Design and Scale-Up

“…Model-based approaches in crystallization utilize population balance modeling to describe the desired system and provide in silico process optimization. Coupled first-principles modeling of crystallization and filtration approaches has been demonstrated in the literature to consider the impacts of filtration operation based on the crystallization method. , Despite the versatility of a mb-QbC approach, robust process modeling often requires careful testing and validation to obtain quality data and adequate parameters to describe the process.…”

Plant-Wide Control System Design of an Alkylation Process Using Integrated Framework of Simulation, Heuristics, and Optimization

“…For example, SOC and IFSH have been applied to HDA, styrene, and ammonia synthesis processes. − Application of PWC methodologies to industrial processes is of interest to test the effectiveness of the proposed methodology and to compare different PWC system design methodologies. From PWC perspective, apart from HDA, styrene, and ammonia synthesis processes, researchers have studied several other processes such as biodiesel process. − …”