2018
DOI: 10.22159/ajpcr.2018.v11i11.27204
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Analytical Method Development and Validation of Atomoxetine Hydrochloride Using Rapid High-Performance Liquid Chromatographic Technique

Abstract: Objective: A simple, novel, sensitive, rapid high-performance liquid chromatographic (RP-HPLC) method has been developed and validated for quantitative determination of atomoxetine HCl (ATH) in bulk and formulations.Methods: The chromatographic development was carried out on RP-HPLC. The column used as Xterra RP 18 (250 mm × 4.6 mm, 5 μ particle size), with mobile phase consisting of methanol: water 80:20 V/V. The flow rate was 1.0 mL/min and the effluents were monitored at 270 nm.Results: The retention time w… Show more

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Cited by 3 publications
(3 citation statements)
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“…In order to validate our homemade code (2D), written in Fortran language, we confronted our numerical results with those de Rahman et al [4] relating to a Newtonian fluid filling a square enclosure with a heat-conducting obstacle.…”
Section: Code Validationmentioning
confidence: 99%
See 1 more Smart Citation
“…In order to validate our homemade code (2D), written in Fortran language, we confronted our numerical results with those de Rahman et al [4] relating to a Newtonian fluid filling a square enclosure with a heat-conducting obstacle.…”
Section: Code Validationmentioning
confidence: 99%
“…Because of its involvement in different industrial systems, such as the cooling of electrical components, thermal comfort in buildings and thermal losses in solar collectors. The ventilated cavity with obstacles is one of the configurations that has attracted the interest of researchers in recent decades; examples include the work of Rahman et al [1][2][3][4] between 2006 and 2012, Boutra et al [5], Bilgen and Yamane [6] in 2004, and Mamun et al [7] in 2010.…”
Section: Introductionmentioning
confidence: 99%
“…HCl, the molecular formula is C 17 H 21 NO. HCl and the molecular weight is 291.82 g/mol [40,41]. ATX.…”
Section: Atxmentioning
confidence: 99%