Analytical methods applied in preparation of radiolabelled proteins and antibodies

Abstract

The concept of application of the radiolabelled antibodies in medicine has already proved its vitality. It is obvious that the synthesis and characterisation of intermediates and final products necessitate utilisation of wide variety of analytical methods. In this work we present our inceptive results we obtained in the development of chromatographic and spectrometric methods designated for routine analytical control of the synthetic procedure applicable in post-labelling synthesis of radiolabelled proteins/antibodies.