Analytical Methods for Nanomaterial Determination in Biological Matrices

Abstract

Nanomaterials are materials in which at least one of the three dimensions ranges from 1 to 100 nm, according to the International Organization for Standardization (ISO). Nanomaterials can be categorized according to various parameters, such as their source, their shape, and their origin. Their increasing use in industrial settings, everyday items, electronic devices, etc. poses an environmental and biological risk that needs to be assessed and appropriately addressed. The development of reliable analytical methods for both characterization and quantification of nanomaterials in various matrices is essential. This review summarized the recent trends in analytical methodologies for the characterization and determination of nanoparticles in biological matrices.

Antibacterial nanocomposite of chitosan/silver nanocrystals/graphene oxide (ChAgG) development for its potential use in bioactive wound dressings

“…Despite there are several characterization techniques for the determination of the presence of nanometric crystals such as Transmission Electron Microscopy (TEM), X-ray Diffraction (XRD), Atomic Force Microscopy (AFM), Dynamic Laser Scattering (DLS), Small-Angle X-ray Scattering (SAXS), amongst others 20 , TGA also provides important information about the thermal stability and kinetic information of the compounds adding evidence of the incorporation of the silver nanocrystals (AgNCs) to the sample 21 . The obtention of silver nanostructures can be seen by thermal analysis such as TGA, on account of the high thermal resistance of silver nanocrystals.…”

Characterization of Nanoparticles in Antimicrobial Coatings for Medical Applications—A Review

“…Acoustic spectroscopy AS [51][52][53] Analytical electron microscopy AEM [54,55] Asymmetric flow field-flow fractionation AF 4 [56,57] Atmospheric pressure photo-ionization mass spectrometry APPI-MS [58,59] Atomic force microscopy AFM [60,61] Capillary electrophoresis CE [62,63] Confocal laser scanning microscopy CLSM [64,65] Cross-flow filtration CFF [66,67] Table 2. Cont.…”

Atomic spectrometry update: review of advances in the analysis of clinical and biological materials, foods and beverages

“…The team of Clases provided two comprehensive reviews 15,16 of the applications of ICP-MS in the biomedical eld, discussing both current practices and future directions, whereas Silva et al 17 devoted their efforts to cover all aspects of single cell ICP-MS (scICP-MS) for biomedical applications. Vladitsi et al 18 summarised the recent trends and criticalities of analytical methodologies for the characterisation and quanti-cation of NPs in biological matrices (Section 5).…”

“…In this Update, we report three papers addressing general issues in NP measurements . A review 18 summarised the recent trends in analytical methodologies for the characterisation and quantification of NPs in biological matrices. Based on the analysis of 60 publications, over the period 2007–2018, the authors described the applications of techniques for the determination of the different characteristics of NPs, such as AAS, DLS, FFF, FTIR, HPLC, GC-LC-MS, ICP-MS, SEM, SIMS, TEM, UV-VIS and XRD.…”