Analytical methods for the determination of bisphenol A in food

Ballesteros‐Gómez, Ana; Rubio, Soledad; Pérez‐Bendito, Dolores

doi:10.1016/j.chroma.2008.06.037

Cited by 373 publications

(182 citation statements)

References 128 publications

Supporting

Mentioning

171

Contrasting

Unclassified

Order By: Relevance

“…It has also been used as an inert ingredient in pesticides, antioxidants and polyvinyl chloride stabilizer [2]. Recently, BPA has received considerable attention due to its endocrine disrupting activity and possible toxic impact on environment [3][4][5]. BPA levels in the g/L range have been found in biological, food and water samples [6,7].…”

Section: Introductionmentioning

confidence: 99%

Laccase biosensor based on screen-printed electrode modified with thionine–carbon black nanocomposite, for Bisphenol A detection

Portaccio

Tuoro

Arduini

et al. 2013

Electrochimica Acta

145

View full text Add to dashboard Cite

a b s t r a c tThe relevance of Bisphenol A (BPA) in human health is well-known. For this reason we designed and developed a biosensor based on a bionanocomposite (laccase-thionine-carbon black)-modified screenprinted electrode. Thionine, a commercially available dye, was used as electrochemical mediator coupled with a nanostructured carbon black. By means of cyclic voltammetry, the interaction of thionine adsorbed on modified screen printed electrode with laccase/BPA reaction products has been studied. In addition, the immobilization of laccase by physical adsorption on the surface of thionine-carbon black modified screen printed electrodes was investigated. The response of the biosensor has been optimized in terms of enzyme loading, pH and applied potential reaching a linear concentration range of 0.5-50 M, a sensitivity of 5.0 ± 0.1 nA/M and a limit-of-detection (LOD) of 0.2 M. The developed biosensor has been also challenged in tomato juice samples contained in metallic cans where release of BPA due to the epoxy resin coating can be assumed. A satisfactory recovery value comprised between 92% and 120% was obtained.

show abstract

Section: Introductionmentioning

confidence: 99%

Laccase biosensor based on screen-printed electrode modified with thionine–carbon black nanocomposite, for Bisphenol A detection

Portaccio

Tuoro

Arduini

et al. 2013

Electrochimica Acta

145

View full text Add to dashboard Cite

show abstract

“…Some hazards and adverse influences have been identified in model animals exposed to low doses of BPA even much lower than the regulated safe dose levels [5]. Meanwhile, complicated matrix effects make the residue analysis of BPA face crucial challenges [6]. So, it is urgently required to develop simple, fast and high sensitive methods for identifying the presence and determining the levels of BPA.…”

Section: Introductionmentioning

confidence: 99%

Thermosensitive molecularly imprinted polymers on porous carriers: Preparation, characterization and properties as novel adsorbents for bisphenol A

Dong

Xiong

et al. 2014

Talanta

View full text Add to dashboard Cite

a b s t r a c tThermosensitive molecularly imprinted polymers (T-MIPs) on porous carriers were prepared via the synergy of dual functional monomers of 4-vinylpyridine (VP) and N-isopropylacrylamide (NIPAM), for selective recognition and controlled adsorption and release of bisphenol A (BPA) by the temperature regulation. The porous polymer supporter was synthesized by multistep swelling of polystyrene and then both the NIPAM with temperature responsiveness and the basic monomers of VP were grafted on them in a simple way. The resultant T-MIPs showed high binding capacity, fast kinetics, and the adsorption processes were found to follow Langmuir-Freundlich isotherm and pseudo-second-order kinetic models. The adsorption capacity increased slightly along with the rise of temperature (such as 20 1C) under lower critical solution temperature (LCST, 33 1C) and decreased fast above LCST (such as 50 1C). Subsequently, the T-MIPs were employed as novel adsorbents for selective solid-phase extraction (SPE) of BPA from seawater and yogurt samples. Satisfying recoveries in the range of 94.83-98.47% were obtained with the precision of 3.21% at ambient temperature (20 1C). Through 6 adsorption-desorption cycles, the reusable T-MIPs exhibited a good recoverability with the relative standard error within 9.8%. The smart T-MIPs provided great potentials for selective identification, adsorption/release and removal of BPA by simple stimuli responsive regulation.

show abstract

“…In any case, these concentrations were far below the current specific migration limit (600 µg kg −1 ) fixed by the European Commission for BPA, and similar to those found by different groups worldwide. 11,12 As far as is referred to BPA in the liquid portions of cans, Brotons et al…”

Section: Analysis Of Bpa In Canned Peas By Elisa and Hplcmentioning

confidence: 99%

“…12 These methods are highly sensitive and specific but they require sophisticated equipment and may be laborious, particularly as regards to sample treatment. Immunoassays offer an inexpensive and quick alternative or complement to traditional chromatographic methods because they are easy to perform and do not require complex instruments.…”

Section: Introductionmentioning

confidence: 99%

Validation of an immunoassay for fast screening of bisphenol A in canned vegetables

2013

View full text Add to dashboard Cite

The effects of BPA exposure on human health are an issue of concern and controversy. In the present work, the validation for the first time of a monoclonal antibody-based enzyme-linked immunoassay (ELISA) for BPA determination in canned vegetables is described, using HPLC as the reference method. From a collection of monoclonal antibodies, a high-sensitivity immunoassay was selected on the basis of its tolerance to organic solvents and the influence of matrix effects. This ELISA displayed a limit of detection of 3 µg kg ). In all samples, BPA concentration was significantly lower than the specific migration level of 600 µg kg −1 established by the European Commission. Therefore, the ELISA herein validated constitutes a sensitive, fast, and high-throughput technique for BPA screening in canned vegetables.

show abstract

Analytical methods for the determination of bisphenol A in food

Cited by 373 publications

References 128 publications

Laccase biosensor based on screen-printed electrode modified with thionine–carbon black nanocomposite, for Bisphenol A detection

Laccase biosensor based on screen-printed electrode modified with thionine–carbon black nanocomposite, for Bisphenol A detection

Thermosensitive molecularly imprinted polymers on porous carriers: Preparation, characterization and properties as novel adsorbents for bisphenol A

Validation of an immunoassay for fast screening of bisphenol A in canned vegetables

Contact Info

Product

Resources

About