This paper presents an experimental and numerical analysis of the response of a scaled double-bottom structure with high and penetrated girders and floors impacted vertically by a rock-shaped indenter. The specimen, scaled from the bottom structure of the power-battery cabin of a new energy ship, is struck by a spherical indenter. The special double-bottom structure is designed to protect the power batteries and to facilitate heat dissipation. The experimental overall impact response, vibration acceleration, and stress of the inner bottom plate are measured in order to evaluate the impact environment in the target cabin. The investigation provides valuable information to evaluate the safety of power-battery cabins in a ship grounding scenario. The experimental results show good agreement with the finite element analyses using the explicit LS-DYNA software. The numerical analysis outlines the influence of the structural openings on the impact response and also the effect of battery mass and striking velocity on the impact environment in the target cabin.