Analytical solution to localize pacemaker sites and determine conduction characteristics in excitable tissues

Abstract

Absrracr-In excitable tissues with spontaneous electrical activity (cardiac and smooth muscles), the site of the pacemaker and the direction and velocity of propagation we visualized by electrical mapping, i.e. the simultaneous recording of electrical activities by an array of many electrodes applied to the tissue and the subsequent follow up of the timing of the electrical signals in each electrogram. This paper describes an analytical method for pacemaker localization and the determination of the instantaneous velocity and direction of propagation along biological tissues. Data of electrical slow wave conduction from the rabbit small intestine are presented as an illustration.