Analyzing Indole-fused benzooxazepines as inhibitors of apoptosis pathway-related proteins using multifaceted computational medicinal chemistry

Phenoxaphosphonium Mixed Ylides in Ring Expansion Reaction

“…Seven-membered heterocyclic systems are prevalent in numerous biologically active natural products and hold promise as scaffolds in medicinal chemistry . Their higher rigidity compared to acyclic compounds often results in improved binding affinity to biological receptors .…”