2024
DOI: 10.3389/fimmu.2024.1423776
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Anandamide modulation of monocyte-derived Langerhans cells: implications for immune homeostasis and skin inflammation

Zsófia Pénzes,
Dorottya Horváth,
Petra Molnár
et al.

Abstract: IntroductionThe endocannabinoid system (ECS), named after the chemical compounds found in the cannabis plant, is a regulatory network of neurotransmitters, receptors, and enzymes that plays crucial roles in skin health and disease. Endogenous ligands of the ECS, called endocannabinoids, have proven to be important regulators of immune responses. One of the most prevalent endocannabinoids, arachidonoylethanolamide (also known as anandamide), is known for its anti-inflammatory effects. Langerhans cells (LCs) are… Show more

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