Anaphylaxie de l'enfant et de l'adolescent: à propos de 44 patients âgés de 2 mois à 15 ans

Marguet, Christophe; Couderc, L.; Blanc, Thomas; Amar, Rachida Mohamed; Leloet, C; Feray, Dagmara; Mallet, E.

doi:10.1016/s0929-693x(99)80250-4

Cited by 19 publications

(5 citation statements)

References 34 publications

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“…Moreover, asthma could be caused by the conjunction of factors associated with ingestion, such as exercise, or inhalation of pollen in sensitized children (28). The frequency of acute food‐induced asthma in the spectrum of allergic emergencies has been highlighted (11, 29). Asthma is the main cause of death due to food anaphylaxis (5, 31–33).…”

Section: Discussionmentioning

confidence: 99%

“…In recent years, food allergy has been characterized by an increase in prevalence, an increase in multiple allergies, and an increase in severe reactions such as anaphylactic shock, laryngeal angioedema, and severe acute asthma (1–12). In children, secondary prevention is necessary, entailing an elimination diet and the availability of injectable epinephrine, possibly complemented by inhaled β‐agonists and corticosteroids.…”

mentioning

confidence: 99%

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Food anaphylaxis in schools: evaluation of the management plan and the efficiency of the emergency kit

Moneret‐Vautrin¹,

Kanny²,

Morisset³

et al. 2001

Allergy

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The frequency of respiratory symptoms during oral challenge tests was confirmed by the frequency of asthmatic reactions within the follow-up period. The role of hidden allergens and of misleading labeling validates the need for PCPs in the case of peanut and tree nut allergies, past history of severe reactions, multiple food allergies, reactions to a low dose in DBPCFCs, and asthmatic reactions to foods. This study provides encouraging data on the usefulness of PCPs and confirms the need for thorough instruction and training of the school staff in dealing with allergic emergencies. Addition of a beta-agonist spray to the emergency kit is suggested.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Food anaphylaxis in schools: evaluation of the management plan and the efficiency of the emergency kit

Moneret‐Vautrin¹,

Kanny²,

Morisset³

et al. 2001

Allergy

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“…Food allergy may be becoming more common in childhood, but we do not know how common severe reactions are. The few relevant studies are based on a small number of children in studies of food‐allergic reactions in people of all ages 1–5 or are case series of children 6, 7. Epidemiological studies of severe reactions are needed, and in an earlier paper 8 we reported deaths from a UK survey between 1990 and 2000; one child under 16 died each year, and the risk of a food‐allergic child dying from a food‐allergic reaction was about 1∶800 000 per year, the child with asthma being probably at higher risk.…”

Section: Introductionmentioning

confidence: 99%

Severe food‐allergic reactions in children across the UK and Ireland, 1998–2000

et al. 2005

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Aim: Medical and lay concerns about food allergy are increasing. Whilst food allergy may be becoming more common, fatal reactions to food in childhood are very rare and their rate is not changing. We sought to establish how common severe reactions are. Methods: Prospective survey, 1998 to 2000, of hospital admissions for food‐allergic reactions—conducted primarily through the British Paediatric Surveillance Unit, covering the 13 million children in the United Kingdom and Ireland. Results: 229 cases reported by 176 physicians in 133 departments, yielding a rate of 0.89 hospital admissions per 100 000 children per year. Sixty‐five per cent were male, 41% were under 4 y and 60% started at home. Main allergens were peanut (21%), tree nuts (16%), cow's milk (10%) and egg (7%). Main symptoms were facial swelling (76%), urticaria (69%), respiratory (66%), shock (13%), gastrointestinal (4%). Fifty‐eight cases were severe. Three were fatal, six near fatal, and 8 of these 9 had asthma with wheeze being the life‐threatening symptom. Three near‐fatal cases received excess intravenous epinephrine. None of the non‐fatal reactions resulted in mental or physical impairment. Seven of 171 non‐severe and 6/58 severe cases might have had a worse outcome if epinephrine auto‐injectors had been unavailable. Six of the severe cases might have benefited if auto‐injectors had been more widely prescribed. Conclusion: In the United Kingdom and Ireland, the incidence of severe reactions is low. The study highlights that: asthma is a strongly significant risk factor for a severe reaction and therefore warrants optimal management; severe wheeze is a prominent feature of severe reactions and warrants optimal management; intravenous epinephrine should be used with great care if needed. Epinephrine auto‐injectors do not always prevent death, but our study design and data do not allow a definite statement about whether overall they are beneficial.

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“…The review was based on observational studies that included cohort, 3,5,7,9,[11][12][13][14][15][16][17][18][19][20][25][26][27][28][29][30][31][32][33] cross-sectional, 4,6,8,[34][35][36][37][38][39] and registry studies assessing the incidence or prevalence of recurrence of anaphylaxis due to cow's milk and/or the incidence of fatal anaphylaxis due to cow's milk. We only accepted studies reporting at least 1 year of follow-up, as this was the period when most recurrences were reported in some studies.…”

Section: Study Selection Criteriamentioning

confidence: 99%

“Frequency of fatal and recurrent anaphylaxis due to COW'S milk: A systematic review and meta‐analysis of observational studies”

Pérez-Codesido

Grifol-Clar

Petrone

et al. 2023

Pediatric Allergy Immunology

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Cow's milk allergy (CMA) is one of the most common food allergies in infants and young children. Immune reactions in CMA are categorized as immunoglobulin E (IgE)-mediated, non-IgE-mediated, and mixed (IgE combined with non-IgE). CMA can result in anaphylactic reactions. 1 As in other food allergies, anaphylaxis caused by cow's milk is a potentially life-threatening allergic reaction, and some patients experience recurrences even when CMA is identified in the initial reaction.Studies performed in diverse populations have assessed the epidemiology of CMA. 1,2 However, community-based incidence

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Anaphylaxie de l'enfant et de l'adolescent: à propos de 44 patients âgés de 2 mois à 15 ans

Cited by 19 publications

References 34 publications

Food anaphylaxis in schools: evaluation of the management plan and the efficiency of the emergency kit

Food anaphylaxis in schools: evaluation of the management plan and the efficiency of the emergency kit

Severe food‐allergic reactions in children across the UK and Ireland, 1998–2000

“Frequency of fatal and recurrent anaphylaxis due to COW'S milk: A systematic review and meta‐analysis of observational studies”

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