2004
DOI: 10.1097/01.all.0000136762.89313.0b
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Anaphylaxis: can we tell who is at risk of a fatal reaction?

Abstract: Most fatal anaphylactic reactions are unpredictable. The appropriate management after recovery from a severe reaction may be protective against a fatal recurrence. An accurate identification of the cause and effective avoidance is a crucial part of this management, together with effective treatment of asthma for those with food allergy, immunotherapy for sting allergy, the avoidance of drugs that potentiate anaphylaxis, and effective training in self-treatment.

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Cited by 297 publications
(256 citation statements)
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References 32 publications
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“…It is now generally recognized that failure to incorporate sex and gender in research designs can result in failures of both effectiveness and efficiency (76). The new paradigm of evidenced-based medicine has underscored this awareness and, Ôfuelled the debate on the limited generalizability of findings [that do not take sex and gender into account] in clinical researchÕ (77).…”
Section: Implications For Research Clinical and Public Health Practicementioning
confidence: 99%
See 1 more Smart Citation
“…It is now generally recognized that failure to incorporate sex and gender in research designs can result in failures of both effectiveness and efficiency (76). The new paradigm of evidenced-based medicine has underscored this awareness and, Ôfuelled the debate on the limited generalizability of findings [that do not take sex and gender into account] in clinical researchÕ (77).…”
Section: Implications For Research Clinical and Public Health Practicementioning
confidence: 99%
“…Secondly, the Global Forum for Health Research (76) suggest that more work is needed to disentangle the links between biological sex and social gender and their relationship with wider determinants of health. For example, many campaigns are targeted at women because of their perceived role as ÔcaregiversÕ (77), while ignoring women's specific concerns, and, as a byproduct, fostering the belief in men that health promotion messages are not relevant to them.…”
Section: Implications For Research Clinical and Public Health Practicementioning
confidence: 99%
“…Systemic anaphylaxis is a relatively rare occurrence, with a lifetime prevalence estimated at 0·05-2% [3]. According to recent epidemiological data, the rate of fatal anaphylaxis ranges from 2 to 20% of cases [4].…”
Section: Introductionmentioning
confidence: 99%
“…The severity of subsequent allergenic reactions cannot be predicted from symptoms reported during initial reactions Pumphrey 2004;Vander Leek et al 2000). Extrinsic factors such as medical and drug history or exercise may enhance the absorption of allergenic protein.…”
Section: Role Of Pal In Accidental Exposures To Allergensmentioning
confidence: 99%