Anaphylaxis during cardiac surgery for hypertrophic cardiomyopathy: patholophysiologic and therapeutic considerations

In response to: Anaphylaxis during cardiac surgery for hypetrophic cardiomyopathy: pathophysiologic and therapeutic considerations

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We are most appreciative for the comments from Dr. Nicholas G. Kounis [1] and his colleagues regarding our recent publication describing the challenging case of anaphylactic shock in patients suffering from hypertrophic obstructive cardiomyopathy (HOCM) scheduled for surgical treatment, namely myectomy [2] Their letter raises several important concerns regarding anaphylaxis in anaesthesia and particularly in patients with HOCM. Before we address each point, we would like to mention that several topics discussed by authors were mentioned in our case report but could not be described in detail due to space limitations.

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