Anaphylaxis following intravenous ranitidine: A rare adverse reaction of a common drug

Chopra, Deepti; Arora, Pooja; Khan, Shamimullah; Dwivedi, Shridhar

doi:10.4103/0253-7613.129334

Cited by 12 publications

(6 citation statements)

References 7 publications

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“…This is the first case of anaphylaxis to ranitidine in pediatric age; anyway, both treatment and timing of presentation are the same as those reported in the literature [1]. …”

Section: Discussionmentioning

confidence: 77%

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Anaphylaxis to Intravenous Ranitidine in a Child

Mori

Barni²,

Pecorari³

et al. 2015

Pharmacology

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“…This is the first case of anaphylaxis to ranitidine in pediatric age; anyway, both treatment and timing of presentation are the same as those reported in the literature [1]. …”

Section: Discussionmentioning

confidence: 77%

“…Recently, a review collecting all reported cases of anaphylaxis to ranitidine has been published [1]. …”

Section: Introductionmentioning

confidence: 99%

Anaphylaxis to Intravenous Ranitidine in a Child

Mori

Barni²,

Pecorari³

et al. 2015

Pharmacology

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“…Hypersensitivity reactions are unusual, most of them are immediate type reactions, usually expressed as mild manifestations such as pruritus or acute maculopapular eruptions without other systemic symptoms [17,18]. Nonetheless, severe reactions such anaphylaxis or angioedema [15][16][17] have been reported.…”

Section: Discussionmentioning

confidence: 99%

Maculopapular delayed exanthema due to ranitidine

Hernández¹,

González²,

Vidal³

et al. 2020

Ann Dermatol Res

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Ranitidine is a widely used drug in Europe and its intake is usually well tolerated. Hypersensitivity reactions due to ranitidine are uncommon. The immediate mild reactions type are the most prevalent. In some special cases a delayed type reaction such as contact dermatitis or severe reactions with systemic involvement have been reported. In the present paper, a case report of a 78-year old patient who experienced a maculopapular eruption after 7 days of oral treatment with ranitidine is described. Patch tests were performed twice with ranitidine with positive results confirming the diagnosis. In order to discard a double sensitization and a possible cross-reactivity phenomenon, patch test was performed once with famotidine, with a negative result. This is the first maculopapular exanthema reported as type IV hypersensitivity reaction to ranitidine confirmed by patch testing. Moreover, there are only two reported cases showing a double sensitization to ranitidine and to other H2-receptor antagonists by patch testing after a delayed reaction due to ranitidine, the other being H2-receptor antagonists involving cimetidine and nizatidine, not famotidine.

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“…Various authors have reported ranitidine-induced anaphylaxis. [ 4 ] Antonicelli et al . in 2012 and Sripriya et al .…”

Section: Discussionmentioning

confidence: 99%

Ranitidine-induced perioperative anaphylaxis: A rare occurrence and successful management

2016

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Perioperative anaphylaxis is a rare and catastrophic event. Anaphylaxis during perioperative period changes the entire management plan for the patient. Since a large number of drugs are administered to the patient during the short span of time, it becomes difficult to identify the culprit drug. This has an impact on the management of the patients who have to undergo surgery. Ranitidine is considered a safe drug used in perioperative period; however, rarely it can lead to perioperative anaphylaxis. We present one such case of ranitidine-induced perioperative anaphylaxis which was successfully managed by early diagnosis and avoidance of drug.

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Anaphylaxis following intravenous ranitidine: A rare adverse reaction of a common drug

Cited by 12 publications

References 7 publications

Anaphylaxis to Intravenous Ranitidine in a Child

Anaphylaxis to Intravenous Ranitidine in a Child

Maculopapular delayed exanthema due to ranitidine

Ranitidine-induced perioperative anaphylaxis: A rare occurrence and successful management

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