Anaphylaxis

Sim, Tommy C.

doi:10.1080/00325481.1992.11701498

Cited by 7 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, platelets, neutrophils, eosinophils, lymphocytes, monocytes, mast cells and basophils are recruited to the area. These newly recruited cells in turn release secondary mediators of anaphylaxis such as histamine releasing factor, major basic protein and lysosomal enzymes causing more inflammation and tissue destruction 8,26 . A further wave of mast cell degranulation is induced leading to a vicious cycle of ongoing inflammation associated with increased vascular permeability 24 .…”

Section: Mechanisms Of Anaphylactic Shockmentioning

confidence: 99%

See 1 more Smart Citation

Anaphylactic shock: mechanisms and treatment

Brown¹

1994

Emergency Medicine

View full text Add to dashboard Cite

This paper reviews the mechanisms of anaphylactic shock in terms of the immunoglobulin and non‐immunoglobulin triggering events; and the cellular events based on the rise in intracellular cyclic AMP and calcium that release preformed granule associated mediators and the rapidly formed, newly synthesised mediators predominantly based on arachidonic acid metabolism. These primary mediators recruit other cells with the release of secondary mediators that either potentiate or ultimately curtail the anaphylactic reaction. The roles of these mediators in the various causes of cardiovascular collapse are examined. The treatment of anaphylactic shock involves oxygen, adrenaline and fluids. The importance and safety of intravenous adrenaline are discussed. Combined H1 and H2 blocking antihistamines and steroids have a limited role. Glucagon and other adrenergic drugs are occasionally used, and there are several new experimental drugs.

show abstract

Section: Mechanisms Of Anaphylactic Shockmentioning

confidence: 99%

“…For instance, the British National Formulary recommends 0.5 to 1.0mg or 1/2 to 1 ml of 1 in 1,000 adrenaline intramuscularly as the standard initial adrenaline regime in anaphylaxis 48 . In the USA, 0.3 to 0.5mg of 1 in 1,000 adrenaline subcutaneously is recommended 3,14,26 . In Sweden, 0.5 to 0.8mg subcutaneously 49 .…”

Section: Treatment Of Anaphylactic Shockmentioning

confidence: 99%

Anaphylactic shock: mechanisms and treatment

Brown¹

1994

Emergency Medicine

View full text Add to dashboard Cite

show abstract

Anaphylaxis. A review of 266 cases

Kemp

Lockey²,

Wolf³

et al. 1995

Archives of Internal Medicine

159

View full text Add to dashboard Cite

(1) Atopy is common in subjects who experience anaphylaxis, regardless of its origin; (2) crustaceans and nonsteroidal anti-inflammatory drugs are the most common food and medication groups, respectively, thought to cause anaphylaxis; (3) causative agents can be identified for two thirds of the subjects, and recurrent attacks are the rule; and (4) subjects with idiopathic anaphylaxis are more likely to carry epinephrine for self-administration than those with identifiable causes.

show abstract

Anaphylaxis and Anaphylactoid Reactions

Fisher¹

1998

Family Medicine

View full text Add to dashboard Cite

Anaphylaxis

Cited by 7 publications

References 25 publications

Anaphylactic shock: mechanisms and treatment

Anaphylactic shock: mechanisms and treatment

Anaphylaxis. A review of 266 cases

Anaphylaxis and Anaphylactoid Reactions

Contact Info

Product

Resources

About