Anastomotic Leak After Colonic Resection

Clinical anastomosis leakage and associated factors among patients who had intestinal anastomosis in northwest referral hospitals, Ethiopia

“…Although there were some variations in the definition of anastomotic leakage, it was defined as the existence of leakage signs, and confirmed by radiographic examination. The leakage signs included leukocytosis, peritonitis, abdominal pain, tenderness, fever, fecal discharge from the pelvic drain, and pelvic abscess [1]. Anastomotic leakage (AL) has three grades, Grade A anastomotic leakage requiring no active therapeutic intervention, Grade B anastomotic leakage requiring active therapeutic intervention but manageable without re-laparotomy, and Grade C anastomotic leakage which is so-called clinical anastomotic leakage is a severe type of AL requiring re-laparotomy [2].…”

“…Surgical-related risk factors such as the location of anastomosis, laparoscopic, and open approaches and handsewn versus stapled anastomoses have been shown to be directly related to the risk of a leak. Patient risk factors such as male gender, diabetes (perioperative hyperglycemia, and elevated hemoglobin A1c), American society of anesthesiologists score �3, older age, smoking, serum albumin <4, weight loss, anemia, blood transfusion, chemo-radiation, perianastomotic drain placement, mechanical bowel preparation, tumor size, increased operative time, emergency surgery, preoperative chemotherapy, intra-operative transfusion were significantly associated with increased risk of AL while pelvic drain resulted in decreased risk of AL [1,7,8].…”