2005
DOI: 10.1111/j.1463-1318.2005.00870.x
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Anastomotic leak following mesorectal excision for rectal cancer: true incidence and diagnostic challenges

Abstract: The incidence of anastomotic leakage seemed acceptable when compared with other series. Fifty per cent of the leaks were silent. CRR and CT may be false negative and immediate treatment should be started if clinical signs are highly suggestive of leak, irrespective of radiological findings CT was not more accurate than CRR in detecting anastomotic leak.

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Cited by 95 publications
(52 citation statements)
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“…The leak of the colorectal anastomosis is the most frequent complication of the surgery for the treatment of rectal cancer, and the reported incidence of clinical leakage varies from 2.6% to 26.2% (11% on 24,845 patients in a recent Cochrane systematic revision) [3,9,[22][23][24].…”
Section: Discussionmentioning
confidence: 99%
“…The leak of the colorectal anastomosis is the most frequent complication of the surgery for the treatment of rectal cancer, and the reported incidence of clinical leakage varies from 2.6% to 26.2% (11% on 24,845 patients in a recent Cochrane systematic revision) [3,9,[22][23][24].…”
Section: Discussionmentioning
confidence: 99%
“…Hartmann's operation is preferred by many authors as the ''gold standard'' technique when sepsis is present [15,16]. The reported postoperative mortality rate associated with anastomotic complications ranges from 6 to 22%, and anastomotic leakage is known to be the most frequent cause of death after low anterior resection [1,3,16].…”
Section: Treatmentmentioning
confidence: 99%
“…Anastomotic leakage is a major cause of morbidity and mortality in patients with rectal cancer undergoing sphincter preserving surgery [1]. Some authors recently advocated that anastomotic leakage is an independent prognostic factor of local recurrence and overall survival [1][2][3].…”
Section: Introductionmentioning
confidence: 99%
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“…Après résection colique ou colorectale, une fistule postopératoire survient dans 5 à 15 % des cas [1,2]. Cette complication induit une morbidité propre : dégradation des résultats fonctionnels, augmentation du taux de sténose anastomotique et de récidive tumorale, mortalité spéci-fique, retard dans la mise en route des traitements complé-mentaires, nécessité de mise en place secondaire d'une stomie avec ses propres conséquences.…”
Section: Introductionunclassified