Anatomical Structure of the Pleura and Mesothelial Cells: What Are the Characteristic Features?

Hiroshima, Kenzo

doi:10.1007/978-981-15-9158-7_7

Cited by 1 publication

(1 citation statement)

References 12 publications

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“…This can be difficult to appreciate histologically 35 . In some circumstances the elastin van Gieson stain may be helpful 36 . Sections from parietal pleura that oppose the chest wall showing histological involvement of skeletal muscle is the best surrogate indicator that the endothoracic fascia has been breached.…”

Section: Core Elementsmentioning

confidence: 99%

Mesothelioma in the pleura, pericardium and peritoneum: Recommendations from the International Collaboration on Cancer Reporting (ICCR)

Klebe,

Judge,

Brcic

et al. 2023

Histopathology

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AimsMesothelioma is a rare malignancy of the serosal membranes that is commonly related to exposure to asbestos. Despite extensive research and clinical trials, prognosis to date remains poor. Consistent, comprehensive and reproducible pathology reporting form the basis of all future interventions for an individual patient, but also ensures that meaningful data are collected to identify predictive and prognostic markers.Methods and resultsThis article details the International Collaboration on Cancer Reporting (ICCR) process and the development of the international consensus mesothelioma reporting data set. It describes the ‘core’ and ‘non‐core’ elements to be included in pathology reports for mesothelioma of all sites, inclusive of clinical, macroscopic, microscopic and ancillary testing considerations. An international expert panel consisting of pathologists and a medical oncologist produced a set of data items for biopsy and resection specimens based on a critical review and discussion of current evidence, and in light of the changes in the 2021 WHO Classification of Tumours. The commentary focuses particularly upon new entities such as mesothelioma in situ and provides background on relevant and essential ancillary testing as well as implementation of the new requirement for tumour grading.ConclusionWe recommend widespread and consistent implementation of this data set, which will facilitate accurate reporting and enhance the consistency of data collection, improve the comparison of epidemiological data, support retrospective research and ultimately help to improve clinical outcomes. To this end, all data sets are freely available worldwide on the ICCR website (www.iccr‐cancer.org/data‐sets).

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Section: Core Elementsmentioning

confidence: 99%