Anatomical Variations of the Occipital Nerves: Implications for the Treatment of Chronic Headaches

Comparison of Cell Number, Viability, Phenotypic Profile, Clonogenic, and Proliferative Potential of Adipose-Derived Stem Cell Populations Between Centrifuged and Noncentrifuged Fat

“…Histologic examination showed patterns of new collagen deposition, local hypervascularity, dermal hyperplasia, and a high correspondence to healthy tissues [3]. The promising results obtained with burn scars led us to extend the use of lipostructure for several pathologic conditions requiring tissue remodeling [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22].…”

The Use of Autologous Fat Grafting for Treatment of Scar Tissue and Scar-Related Conditions

“…39,[45][46][47] The levels of evidence were II in five studies, 33,36,39,41,45 III in seven studies, [23][24][25][26]38,42,44 and IV in 14 studies. 22,23,[28][29][30]32,34,35,37,40,43,[46][47][48] Four randomized controlled trials, 33,36,39,45 16 prospective cohort studies, 22,[25][26][27]29,30,32,34,35,37,38,[41][42][43][44]46 and six retrospective cohort studies …”

“…[12][13][14][15] The mitigating effect of autologous fat grafting on different types of pain was postulated to be a result of changes in the microenvironment and secretion of substances by mesenchymal cells of the graft, which may cause prolonged analgesia. [16][17][18] In general, positive results were reported for all of the treatment objectives. However, one should be aware that there is an inherent bias for publication of positive results.…”

“…The hypothesis is that mesenchymal cells of the graft give prolonged analgesia by changes in the microenvironment and secretion of substances. [16][17][18] The use of autologous fat grafting is used increasingly in common practice, but to date, there is a lack of scientific evidence regarding the effects on scar tissue. 13 Our goal is to systematically review the available literature that describes the effectiveness of autologous fat grafting in the treatment of scar tissue-related symptoms, including the appearance of the scar, skin characteristics, restoration of volume and/or (threedimensional) contour, pain, and itch.…”

Perineural Fat Grafting in the Treatment of Painful Neuromas

“…The biological effects of autologous adipose graft result from neoangiogenesis, 27 inflammatory response modulation, and prevention of scar adherences, 28 probably because of the active role of preadipocytes, multipotent cells, and growth factors.…”