Anatomy, trichome micromorphology and phytochemical profile of Stachys rizeensis R.Bhattacharjee from Turkey

Stachys brachyclada de Noé ex Coss. (Lamiaceae) is a quite rare medicinal plant endemic to the Mediterranean basin. In this study, seven secondary metabolites from a methanol extract of its leaves have been isolated and identified by a combination of chromatographic and spectroscopic methods (1D and 2D NMR experiments and ESIMS analysis). They include one ethyl 4-hydroxybenzoate (1), three acylated flavone glycosides (2-4), one diapigenin derivative (5), and two flavone aglycones (6-7). Stachysetin (5) was found the major compound of the extract (74.0 mg/g of dry matter). Moreover, the produced extract showed the ability in inhibiting the -glucosidase enzyme (IC50 = 13.7 g/mL), in quenching the radical 1,1-diphenyl-2-picrylhydrazyl (EC50 = 74.6 g/mL), and in reducing the intracellular oxidative stress level in Human Dermal Fibroblast (64 % inhibition at 50 g/mL).

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Phytochemical analysis, antioxidant and hypoglycemic activities of a methanol extract fromStachys brachycladade Noé ex Coss. leaves

Lemoui

Picerno

Benyahia

et al. 2023

Natural Product Research

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Anatomy, trichome micromorphology and phytochemical profile of Stachys rizeensis R.Bhattacharjee from Turkey

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Phytochemical analysis, antioxidant and hypoglycemic activities of a methanol extract fromStachys brachycladade Noé ex Coss. leaves

Phytochemical analysis, antioxidant and hypoglycemic activities of a methanol extract fromStachys brachycladade Noé ex Coss. leaves

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