2023
DOI: 10.1093/molehr/gaad017
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Androgen signalling in the ovaries and endometrium

Abstract: Currently, our understanding of hormonal regulation within the female reproductive system is largely based on our knowledge of estrogen and progesterone signalling. However, while the important functions of androgens in male physiology are well known, it is also recognised that androgens play critical roles in the female reproductive system. Further, androgen signalling is altered in a variety of gynaecological conditions, including endometriosis and PCOS, indicative of regulatory roles in endometrial and ovar… Show more

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Cited by 8 publications
(1 citation statement)
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“…AR is a critical hormone involved in the early‐release feedback regulation of the hypothalamus–pituitary–gonadal axis, which is involved in the hormone secretion process of GnRH, FSH, and LH 55 . AR can influence follicle atresia by affecting somatic cell apoptosis or oocyte degeneration, 56 and AR plays an important role in the development and functional activity of the female genital organ.…”
Section: Discussionmentioning
confidence: 99%
“…AR is a critical hormone involved in the early‐release feedback regulation of the hypothalamus–pituitary–gonadal axis, which is involved in the hormone secretion process of GnRH, FSH, and LH 55 . AR can influence follicle atresia by affecting somatic cell apoptosis or oocyte degeneration, 56 and AR plays an important role in the development and functional activity of the female genital organ.…”
Section: Discussionmentioning
confidence: 99%