Androgenic alopecia and insulin resistance: are they really related?

“…However, on contrary these studies in case controlled study from Egypt no association was observed between AGA and insulin resistance in young aged group including both gender [11]. In relation to this study in Nabaie et al study there was no difference in individual components of metabolic syndrome including serum fasting insulin level, fasting blood glucose, serum total cholesterol, triglyceride, high density cholesterol levels (HDL-C) and insulin resistance between the AGA and a control group [12].…”

contrasting

confidence: 46%

The Association between Metabolic Syndrome Components and Hair Loss both Male and Female Individuals

Çakır¹

2013

Hair Therap Transplantat

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In last decade studies have noted that hair loss could be a manifestation of metabolic abnormalities including increased insulin resistance, blood pressure, total cholesterol, triglyceride and decreased insulin sensitivity and HDL-C. Additionally, the recent studies have shown that hair loss have an increased risk for mortality from cardiovascular disease accompanied with metabolic syndrome both in male and female adults. Therefore the patients with hair loss should be detected for metabolic syndrome and metabolic syndrome components and those with metabolic syndrome should be followed up for cardiovascular disease risk.

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“…[910] The association between AGA and MetS may be gender-specific to females. [11] Furthermore, the association of MetS with increasing severity of AGA is inconclusive.…”

Section: Introductionmentioning

confidence: 99%

Association of premature androgenetic alopecia and metabolic syndrome in a young Indian population

Chakrabarty

Hariharan²,

Gowda

et al. 2014

Int J Trichol

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Context:Although evidences for association of androgenetic alopecia (AGA) with metabolic syndrome (MetS) are accruing, inconclusiveness with respect to the gender specificity and differential association of MetS with increasing severity of AGA continues to persist. Furthermore, data specific to Indian settings are relatively sparse.Aims:The present study aimed at assessing the frequency of MetS in individuals with early AGA in Indian settings.Settings and Design:A case-control study was conducted at a trichology clinic in Bengaluru between April 2012 and September 2012 with a total of 85 cases of AGA and 85 age-matched controls.Materials and Methods:The Norwood-Hamilton classification was used to assess the grade of AGA. MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria. Blood pressure, blood glucose, lipid parameters, and body mass index along with anthropometric measurements were assessed in all study participants.Statistical Analysis Used:Chi-square test was used to compare proportions between groups. Means were compared between groups using Student's t-test.Results:MetS was seen in a higher proportion of patients with AGA (43.5%) as compared to the control group (2.4%) and the differences were statistically significant (P < 0.001). As compared to controls, patients with AGA had higher triglycerides (P < 0.001), systolic blood pressure (P < 0.001), diastolic blood pressure (P < 0.001) along with significantly lower high-density lipoprotein cholesterol levels (P < 0.001). Severity of AGA was not associated with MetS.Conclusions:AGA is associated with MetS in male Indian patients aged <30 years. Studies with large sample sizes may be required to conclusively define any putative associations between AGA grades and MetS.

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Androgenic alopecia and insulin resistance: are they really related?

Abstract: Despite previous reports suggesting a link, our study found no significant relationship between insulin resistance and androgenic alopecia. Further studies are warranted.

Cited by 42 publications

References 18 publications

Role of Insulin Resistance in Males with Early Androgenetic Alopecia

Role of Insulin Resistance in Males with Early Androgenetic Alopecia

The Association between Metabolic Syndrome Components and Hair Loss both Male and Female Individuals

Association of premature androgenetic alopecia and metabolic syndrome in a young Indian population

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