Androgenic Control of Phallic Papillae in Hamsters: A Quantitative Analysis Using the Scanning Electron Microscope

Whitsett, J. Mal; Ayer, Mark L.; Muse, Kenneth E.

doi:10.1095/biolreprod23.3.669

Cited by 7 publications

(4 citation statements)

References 13 publications

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“…Penile spines develop by an androgen dependent manner (Whitsett et al ., 1980;Ninomiya et al ., 1984). Such spines have been considered to stimulate physiologically and lead to ovulation of females after mating (Ninomiya et al ., 1984;Bedford et al ., 1997).…”

Section: Discussionmentioning

confidence: 99%

The Morphological and Histological Characters of the Male External Genitalia of the House Musk Shrew, Suncus murinus

et al. 2005

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External genitalia are the reproductive organs necessary for efficient copulation and internal fertilization in various mammalian species. Their morphogeneses display significant morphological and developmental differences among species. The house musk shrew, Suncus murinus (hereafter described as suncus) is a species of the order Insectivora, which has been considered as primitive and one of the earliest eutheria phylogenetically. Comparative anatomical analyses of phylogenetically different mammals will contribute to the better understanding of morphological diversity of external genitalia. This study performed various anatomical and histological analyses concerning the organization of the external genitalia of male suncus. It was shown that the external genitalia of suncus possessed a muscular structure, which we proposed as musculus ischiocavernosus dorsalis of suncus. The musculus ischiocavernosus dorsalis is originated from the inner surface of the tuber ischiadicum and was allocated adjacent to the corpus cavernosum penis. In addition, a pair of alpha-smooth muscle actin positive muscles was located bilaterally to the urethra. This unique morphology of the external genitalia of suncus males may provide a unique model system to investigate genital morphogenesis.

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Section: Discussionmentioning

confidence: 99%

The Morphological and Histological Characters of the Male External Genitalia of the House Musk Shrew, Suncus murinus

et al. 2005

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“…First, counts of penile spines are sometimes used as a sensitive measure of circulating androgen (e.g., Baum et al, 1982;Kierniesky and Gerall, 1973), and such estimates may have reduced reliability if they derive from nonerect specimens or do not take into account the possible variation along the length of the glans in androgen sensitivity of spines. Second, rats (Taylor et al, 1983a), hamsters (Whitsett et al, 19801, and species in five genera of cricetid rodents (Hooper, 1959) have been reported to have more spines at the base than at the tip of the glans. However, the glans and its spines may not be equally erectable along its length.…”

Section: Discussionmentioning

confidence: 99%

Morphology of the erect glans penis in rats under various gonadal hormone conditions

1984

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The scanning electron microscope (SEM) was used to compare erect and nonerect penile glandes of gonadally intact Norway rats (group I) and of castrated rats exposed to the following hormonal conditions: maintained with testosterone (T)-filled Silastic capsules implanted subcutaneously (group T); maintained with implants of estradiol (E) for 8 or 12 days (group E1); maintained with E implants for 10 weeks (group E10); maintained with E implants for 9 weeks, then injected daily with testosterone propionate for 8 or 17 days (group E/T). As in previous SEM depictions of nonerect glandes of intact rats, spines projected toward the base of the glans at a shallow angle from the sulci of deep epithelial folds. In contrast, the folds on erect glandes of groups I and T were completely smoothed, and the spines were themselves erected. The penile cup formed at the distal end of the erect glans also contained spines; these were centrifugally directed at the rim and centripetally directed on the inner surface of the cup. The glandes of group E1 males were similar to those in groups I and T, with the spines showing no disorientation. Males in group E10 lacked spines in the cup and along most of the shaft of the glans, but erection revealed many sharp spines just proximal to the cup and on its rim. In group E/T, no papillae were detectable on the nonerect glandes, but erection revealed many small rounded papillae on the shaft and within the cup. The erection of the spines that occurs on the shaft and in the cup of the erect glans may facilitate previously proposed functions of the spines, including vaginal and cervical stimulation and removal of the copulatory plug. Our perfusion method may also facilitate estimation of the number, size, distribution, and hormonal sensitivity of penile papillae.

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“…Puberty in male deer mice is readily accelerated by a change from a short to a long photoperiod at weaning (Whitsett, Lawton & Miller, 1984b Whitsett, Ayer & Muse (1980). The surface of the penis was examined and micro¬ graphs were prepared at a magnification of 200.…”

Section: General Methodsmentioning

confidence: 99%

“…Histological analysis of testes also supports the view that puberty in males is best regarded as a continuous process (Miller, Whitsett, Vandenbergh & Colby, 1977;Bediz & Whitsett, 1979 Cornified spines are present on the surface of the penis in many species of rodents (Hooper, 1959). In rats and hamsters, at least, the presence of spines in the adult male depends upon exposure to testicular androgen during neonatal life and again in adulthood (Beach & Levinson, 1950;Whitsett et al, 1980 …”

Section: General Methodsmentioning

confidence: 99%

Effect of transitional photoperiods on testicular development and puberty in male deer mice (Peromyscus maniculatus)

Whitsett¹,

Noden²,

Cherry³

et al. 1984

Reproduction

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Androgenic Control of Phallic Papillae in Hamsters: A Quantitative Analysis Using the Scanning Electron Microscope

Cited by 7 publications

References 13 publications

The Morphological and Histological Characters of the Male External Genitalia of the House Musk Shrew, Suncus murinus

The Morphological and Histological Characters of the Male External Genitalia of the House Musk Shrew, Suncus murinus

Morphology of the erect glans penis in rats under various gonadal hormone conditions

Effect of transitional photoperiods on testicular development and puberty in male deer mice (Peromyscus maniculatus)

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