2013
DOI: 10.1155/2013/962349
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Androtherm Application for the Peyronie's Disease

Abstract: Peyronie's disease is characterized by a scarring fibrosis within the tunica albuginea of the penis that could lead to penile length loss, narrowing, curvature, erectile dysfunction, or pain with erection. This problem has recently no appropriate treatment. Our objective is to treat this kind of disease by a new kind of hyperthermia method.

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Cited by 7 publications
(5 citation statements)
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“…The demodulated signal promotes re-establishment of the homeostatic balance of the cells by charging the redistribution (143) and by the effective intracellular reordering of the cytoskeleton (144), giving less opportunity of the cytoskeleton components (structural: tubulin, actin; and dynamical: dynein, kinesin, and myosin) (145) providing intracellular transport to the correct location for the replication of the virus. Patients with penile fibrosis (Peyronie's disease) (146), and palm fibrosis (Dupuytren's contracture) (147) were successfully treated with mEHT. Furthermore, the mEHT treatment on malignant fibrosarcoma also showed a great benefit for the patient (148).…”
Section: Treatment Of Fibrosismentioning
confidence: 99%
“…The demodulated signal promotes re-establishment of the homeostatic balance of the cells by charging the redistribution (143) and by the effective intracellular reordering of the cytoskeleton (144), giving less opportunity of the cytoskeleton components (structural: tubulin, actin; and dynamical: dynein, kinesin, and myosin) (145) providing intracellular transport to the correct location for the replication of the virus. Patients with penile fibrosis (Peyronie's disease) (146), and palm fibrosis (Dupuytren's contracture) (147) were successfully treated with mEHT. Furthermore, the mEHT treatment on malignant fibrosarcoma also showed a great benefit for the patient (148).…”
Section: Treatment Of Fibrosismentioning
confidence: 99%
“…Using the modern achievements of the physiology, oncothermia answers positively on the doubts about the conventional hyperthermia. The experimental and preclinical results are described in other papers presented in this conference [166][167][168][169][170][171][172][173], so I summarize the clinical results only. Remarkable amounts of retrospective and prospective clinical studies are available to indicate the oncothermic effect in humans [174,175].…”
Section: Resultsmentioning
confidence: 99%
“…The mEHT is feasible for treating fibrotic states due to its electric field effect, which could moderate the EMT [337], so we consider it to treat certain fibrotic conditions. The successful anti-fibrotic effect of mEHT is proven for patients with fibrosis of the penis (Peyronie's disease) [338], and fibrosis of the palm (Dupuytren's contracture) [339]. Furthermore, mEHT treatment in Open Journal of Biophysics malignant fibrosarcoma also showed a great benefit to the patient [340].…”
Section: The Hypothesismentioning
confidence: 99%