Anemia considerations when assessing natriuretic peptide levels in ED patients

Karakoyun, İnanç; Çolak, Ayfer; Arslan, Fatma Demet; Hasturk, Aybike Gunaslan; Duman, Can

doi:10.1016/j.ajem.2017.05.048

Cited by 11 publications

(5 citation statements)

References 24 publications

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“…The small number of patients included in the study might explain these results. Furthermore, walking distance test can also be influenced by anemia, as could be NTproBNP level, [26] although we could not find a correlation between these parameters in this study.…”

Section: Journal Of Translational Internal Medicine / Jan-mar 2020 / contrasting

confidence: 74%

Evaluation of cardiac function in patients with sickle cell disease with left ventricular global longitudinal strain

Morissens

Besse‐Hammer

Azerad

et al. 2020

Journal of Translational Internal Medicine

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Background and ObjectivesThe importance of myocardial dysfunction in sickle cell disease (SCD) is currently debated. It is difficult to find a reliable index of function in patients with chronic overload as in SCD. Speckle tracking echocardiography, a new mean of evaluating cardiac function, might be a useful tool in SCD. It has been applied in many fields to detect early cardiac function deterioration, and it is less load dependent compared with other function parameters. Studies in patients with SCD are rare, and the results are conflicting. The present study aimed to determine whether left ventricular global longitudinal strain (LV-GLS) was abnormal in a population of adults with SCD and whether it was correlated with clinical or biological parameters.MethodsWe prospectively enrolled 37 patients and 34 age- and sex-matched healthy controls. Echocardiography was performed in patients and controls.ResultsWe found that the left ventricular diameter and mass were higher and the ejection fraction and longitudinal strain were lower in patients compared with controls. Diastolic dysfunction was uncommon. LV-GLS was abnormal in 21% of the patients. No correlation was observed between strain and clinical or biological parameters.ConclusionsWe concluded that LV-GLS could be a useful tool for evaluating these patients. However, the clinical impact of reduced LV-GLS remains to be determined.

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Section: Journal Of Translational Internal Medicine / Jan-mar 2020 / contrasting

confidence: 74%

Evaluation of cardiac function in patients with sickle cell disease with left ventricular global longitudinal strain

Morissens

Besse‐Hammer

Azerad

et al. 2020

Journal of Translational Internal Medicine

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show abstract

“…However, elevated levels of TnT and NT-proBNP were also found after adjusting for BMI, suggesting that our findings may not merely reflect an increased prevalence of cardiometabolic risk in patients with mediastinitis. It is also important to note that NT-proBNP has been to be affected by other factors such as anemia (23) and renal failure (24) that was not adjusted for in the present study. Furthermore, the prevalence of prior MI was as twice as common in patients with mediastinitis compared with controls.…”

Section: Discussionmentioning

confidence: 94%

Increased levels of NT-proBNP and troponin T 2 years after coronary artery bypass grafting complicated by mediastinitis

Risnes

Aukrust²,

Lundblad³

et al. 2023

Front. Cardiovasc. Med.

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BackgroundMediastinitis after coronary bypass grafting (CABG) increases the risk of the internal mammary artery (IMA) graft obstruction, and has a detrimental effect on long-term survival. The pathogenesis for this increased mortality is poorly understood. In the present study, we aimed to investigate the relationship between mediastinitis and persistently elevated cardiac-specific biomarkers [troponin T (TnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP)] and C-reactive protein (CRP) at mid-term follow-up following CABG.Material and methodsThe epidemiologic design was of an exposed (mediastinitis, n = 41) vs. randomly selected non-exposed (non-mediastinitis) controls (n = 41) cohort. Serum samples for measurements of NT-proBNP, TnT, and CRP were obtained at a median follow up time of 2.7 (range 0.5–5.2) years after CABG surgery.ResultsNT-proBNP (mean 65.0 pg/ml vs. 34.8 pg/ml, p = 0.007) and TnT levels (mean 14.7 ng/L vs. 11.2 ng/L, p = 0.004) were significantly higher in the mediastinitis group than in the control group. Patients with mediastinitis had also higher body mass index (BMI) and were more likely to have diabetes and previous myocardial infarction. There was no difference in serum CRP level between the groups. After controlling for potential confounders (previous myocardial infarction, age, and BMI), the presence of mediastinitis was associated with higher levels of log NT-proBNP (p = 0.02) and log TnT (p = 0.04).ConclusionMediastinitis increases the concentrations of cardiac-specific biomarkers NT-proBNP and TnT at mid-term follow-up, representing persistent myocardial injury and impaired cardiac function.

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“…The small number of patients included in the study might explain these results. Furthermore, walking distance test can also be influenced by anaemia, as could be NTproBNP level (Karakoyun et al , ).…”

Section: Univariate Analysis Results Show Differences Between Scd Andmentioning

confidence: 99%

Added value of speckle tracking in the evaluation of cardiac function in patients with sickle cell disease

et al. 2018

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Anemia considerations when assessing natriuretic peptide levels in ED patients

Cited by 11 publications

References 24 publications

Evaluation of cardiac function in patients with sickle cell disease with left ventricular global longitudinal strain

Evaluation of cardiac function in patients with sickle cell disease with left ventricular global longitudinal strain

Increased levels of NT-proBNP and troponin T 2 years after coronary artery bypass grafting complicated by mediastinitis

Added value of speckle tracking in the evaluation of cardiac function in patients with sickle cell disease

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