2002
DOI: 10.1097/00000421-200208000-00011
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Anemia in Oncology Practice

Abstract: Anemia is common in patients with cancer and is a frequent complication of myelosuppressive chemotherapy. In this study, we investigated the incidence and severity of chemotherapy-induced anemia caused by the most common chemotherapy regimens, including the new generation of chemotherapeutic agents, used in the treatment of the major nonmyeloid malignancies in adults. Five hundred fifty-two patients with histologically proven carcinoma originating from breast (n = 165), lung (n = 128), colon (n = 75), ovary (n… Show more

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Cited by 94 publications
(23 citation statements)
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“…Anemia in cancers is not just due to the disease but also a consequence of chemotherapy 20. In the treatment of anemia of malignancies, EPO was thought to be safe until the EpoR was identified in various types of cancer cells, including breast cancer cells.…”
Section: Discussionmentioning
confidence: 99%
“…Anemia in cancers is not just due to the disease but also a consequence of chemotherapy 20. In the treatment of anemia of malignancies, EPO was thought to be safe until the EpoR was identified in various types of cancer cells, including breast cancer cells.…”
Section: Discussionmentioning
confidence: 99%
“…16 Of all cancers, lymphomas, lung tumors, gynecologic, and genitourinary tumors have the highest incidence of anemia with at least 50%-60% requiring transfusion. 17 Among solid tumors, patients with lung cancer require the highest frequency of transfusion and are typically transfused at higher hemoglobin levels which has been attributed to both older age and suspicion of concurrent pulmonary disease. 11,18 Anemia at baseline prior to initiation of chemotherapy is associated with an increased incidence of CIA and patients with prechemotherapy hemoglobin levels <11 g/dL are more likely to receive a red blood cell transfusion than those with normal baseline hemoglobin levels.…”
Section: Introductionmentioning
confidence: 99%
“…Anemia is in fact considered as a bad prognostic factor for survival regardless of tumor type [2]. Up to 40% of cancer patients are anemic at diagnosis [3, 4] and the frequency even increases following chemotherapy [5]. This incidence varies according to the stage and the tumor type as well as patient age.…”
Section: Introductionmentioning
confidence: 99%