Anemia, intractable vomiting, chronic diarrhea, and syndrome of inappropriate antidiuretic secretion

Abstract

It is very important to suspect Strongyloides infection in a patient presenting with syndrome ofinappropriate antidiuretic secretion as hyperinfection and disseminated disease can be life threatening without antihelmintic therapy.

<b><i>Strongyloides stercoralis</i></b> with Gastroduodenal Involvement and Complicated with SIADH: An Unusual Diagnosis to Consider in Immunosuppressed Patients with Hyperemesis and Eosinophilia

“…The incidence of strongyloidiasis is increasing in many developing countries and it is facilitated by international travel and immigration [3]. It is estimated that about 30–100 million people are infected worldwide [2, 4].…”

“…The lifecycle of S. stercolaris is complex because it completes its entire cycle within the human host [2, 4]. Free-living larvae penetrate the skin and migrate to the lungs via venous circulation [2-4, 6, 7].…”

“…The lifecycle of S. stercolaris is complex because it completes its entire cycle within the human host [2, 4]. Free-living larvae penetrate the skin and migrate to the lungs via venous circulation [2-4, 6, 7]. They break into the alveolar spaces, ascend through the tracheobronchial tree, and are swallowed with sputum [4, 6, 7].…”

“…Free-living larvae penetrate the skin and migrate to the lungs via venous circulation [2-4, 6, 7]. They break into the alveolar spaces, ascend through the tracheobronchial tree, and are swallowed with sputum [4, 6, 7]. After reaching the gastrointestinal tract, they invade the small bowel and live buried in the crypts [2, 3, 6, 7].…”

“…After reaching the gastrointestinal tract, they invade the small bowel and live buried in the crypts [2, 3, 6, 7]. The most affected sites are the duodenum and the upper jejunum, where the larvae develop into adult worms [2-4, 7, 8]. Adult female worms usually reside under the intestinal mucosa, where they shed eggs [3].…”