Anestesia na população negra

Vale, Nilton Bezerra do; Delfino, José

doi:10.1590/s0034-70942003000300013

Cited by 4 publications

(3 citation statements)

References 51 publications

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“…The reasons why black patients received more propofol than non-black patients is unclear; data on differing response rates to propofol based on ethnicity is unconvincing. 32,33 …”

Section: Discussionmentioning

confidence: 99%

Practice patterns of sedation for colonoscopy

Childers

Williams

Sonnenberg

2015

Gastrointestinal Endoscopy

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Background Sedative and analgesic medications have been routinely used for decades to provide patient comfort, reduce procedure time, and improve examination quality during colonoscopy. Objective To evaluate trends of sedation during colonoscopy in the United States Setting Endoscopic data repository of U.S. gastroenterology practices (Clinical Outcomes Research Initiative, CORI database from 2000 until 2013). Patients The study population comprised patients undergoing a total of 1,385,436 colonoscopies. Interventions Colonoscopy without any intervention or with mucosal biopsy, polypectomy, various means of hemostasis, luminal dilation, stent placement, or ablation. Main Outcome Measurements Dose of midazolam, diazepam, fentanyl, meperidine, diphenhydramine, promethazine, and propofol used for sedation during colonoscopy. Results During the past 14 years, midazolam, fentanyl and propofol have become the most commonly used sedatives for colonoscopy. Except for benzodiapenzines, which were dosed higher in women than men, equal doses of sedation were given to female and male patients. Whites were given higher doses than other ethnic groups undergoing sedation for colonoscopy. Except for histamine-1 receptor antagonists, all sedative medications were given at lower doses to patients with increasing age. The dose of sedatives was higher in colonoscopies associated with procedural interventions or of long duration. Conclusions The findings reflect on colonoscopy practice in the United States during the last 14 years, and provide an incentive for future research on how gender and ethnicity influence sedation practices.

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“…The reasons why black patients received more propofol than non-black patients is unclear; data on differing response rates to propofol based on ethnicity is unconvincing. 32,33 …”

Section: Discussionmentioning

confidence: 99%

Practice patterns of sedation for colonoscopy

Childers

Williams

Sonnenberg

2015

Gastrointestinal Endoscopy

View full text Add to dashboard Cite

show abstract

“…Fatores étnicos, dietéticos e sócio-econômicos (fenótipos), facilitadores de lesões microvasculares em órgãos-alvo como cérebro, coração e rins, justificam a maior gravidade da hipertensão arterial sistêmica (HAS) do negro através dos sistemas catecolaminérgicos, renina-angiotensina-calicreí-na renais, canal de sódio, metabolismo lipoprotéico, hormô-nios e taquicininas (genótipo) 1,2, 14,15,[26][27][28][29][30][31] . A alta mortalidade na viagem pelo Atlântico em navios negreiros promoveu uma "seleção natural" dos negros africanos: sobreviveram aqueles cujo organismo fora mais competente em reter sódio e água, isto é, com baixo nível de renina.…”

Section: ) Drogas Anti-hipertensivas Eficazes E Ineficazesunclassified

“…Ethnic, dietary and social-economic factors (phenotypes), facilitators of microvascular lesions in target-organs such as brain, heart and kidneys, justify the increased severity of systemic arterial hypertension (SAH) of blacks through catecholamine, renal renin-angiotensin-calicrein, sodium channels, lipoprotein metabolism, hormones and tachikinines systems (genotype) 1,2, 14,15,[26][27][28][29][30][31] . The high mortality rate when crossing the Atlantic Ocean in slave ships has promoted a "natural selection" of black Africans: those more competent to retain sodium and water, that is, with a low renin level, would survive.…”

Section: ) Effective and Ineffective Anti-hypertensive Drugsmentioning

confidence: 99%