“…11,12,45,[47][48][49] Perioperative mortality trends may initially increase in middleincome countries with increasing access to surgical care, the increased provision of surgery for unwell patients undergoing complex procedures, and more reliable data. 9,11,12,19,29 A 2014 study from Brazil demonstrated this, as 24-hour perioperative mortality increased when compared against the incidence of mortality reported in previous studies. 11,47,50 Anaesthetic-related mortality increases by a factor of 50-100 in low-income countries, but may be 1 000-fold higher in certain poor countries.…”