Anesthetic considerations in scoliosis patient with dopa-responsive dystonia or Segawa’s syndrome

Hasan, Mohd Shahnaz; Leong, KW; Chan, Chris Yin Wei; Kwan, Mun Keong

doi:10.1177/2309499016684743

Cited by 1 publication

(1 citation statement)

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“…The safe use of propofol for intravenous general anesthesia has been reported in non-obstetric patients. [10,11] In a cases series of 12 patients with DRD, the author suggested that both succinylcholine and non-depolarizing muscle relaxants were to be tolerated in these patients. [12] Neostigmine and atropine have been reported to counter atracurium muscle relaxant residue in patients with DRD without significant adverse effects.…”

Section: Discussionmentioning

confidence: 99%

Chloroprocaine 3% for anesthesia during cesarean section in a patient with dopa-responsive dystonia: A case report

Zhou,

Luo

2024

Medicine

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Rationale: Dopa-responsive dystonia (DRD) is a rare autosomal dominant hereditary disorder with a prevalence of 0.5 per million population. The disease is characterized by onset of dystonia in childhood, progressive aggravation of the dystonia with diurnal fluctuation, and complete or near complete alleviation of symptoms with low-dose oral levodopa. The incidence of DRD is low, and only a few publications have described this disorder connected with anesthesia. Patient concerns: We present a case involving a pregnant woman with DRD who continued levodopa/benserazide throughout the pregnancy. The perioperative anesthesia management was described. We used chloroprocaine 3% for epidural anesthesia during cesarean section. Diagnoses: Dopa-responsive dystonia Interventions: Levodopa/benserazide Outcomes: In summary, levodopa/benserazide was continued throughout our patient’s pregnancy with a good obstetric outcome, and chloroprocaine was safely used in epidural anesthesia without deterioration of her dystonic symptoms. Lessons: Chloroprocaine was safely used in epidural anesthesia without deterioration of her dystonic symptoms.

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Section: Discussionmentioning

confidence: 99%