Aneurysm Wall Stress and Tendency to Rupture are Features of Physical Wall Properties: An Experimental Study

Abstract

AAA wall mechanics contribute more significantly to peak wall stress than pressure variations within the system. In particular, increased stiffness (analogous to collagen deposition) significantly increased peak wall stress, which was located at the inflection point rather than at the maximum diameter. Techniques to measure the AAA wall mechanics and the rate of deterioration may predict AAA rupture in the untreated state or in the presence of an endoleak following endovascular repair.

Aortic Customize: A new alternative endovascular approach to aortic aneurysm repair using injectable biocompatible elastomer. An in vitro study

“…We chose to use this method as it was accurate and easy in use, while other, more complicated methods such as infinite model stress analysis 26 were not available to us, and other methods with fixed-strain gauges are not very sensitive and may influence the measurements. 27 As this study was setup as a proof-of-principleexperiment, we were satisfied with approximations of wall stress on a few sites of the aneurysm sac. The important finding is the difference in wall stress, before and after sac filling (Fig 4).…”

Computational analysis of type II endoleaks in a stented abdominal aortic aneurysm model

“…It can be seen that the simulation results are in excellent agreement with the experimental data. Flora et al (2002) measured the wall stress distribution with in vitro latex aneurysm models featuring different wall stiffnesses. Adopting the same model and material properties, the AAA-wall stress was computed for similar flow conditions employing the ANSYS ALE FSI-solver.…”

“…of wall stress between simulation and experimental data(Flora et al, 2002) Comparison between simulation and experimental data.…”

Computational analysis of biomechanical contributors to possible endovascular graft failure

“…It can be seen that the simulation results are in good agreement with the experimental data. Flora et al (2002) investigated the wall stress distribution with in vitro latex aneurysm models consisting of variable wall stiffness under different blood flow conditions. Adopting the same model and material properties, the AAA wall-stress was computed under similar flow conditions, employing again the ANSYS ALE FSI-solver (see Fig.…”