Aneurysma des rechten Ausflußtraktes nach Perikardflickenplastik

Abstract

Among 1022 patients who underwent total repair of tetralogy of Fallot, 252 patients received a pericardial patch of the right ventricular outflow tract (RVOT); and of these 10 subsequently developed an aneurysm of the RVOT. Cardiac catheterization and angiography revealed moderate pulmonary unsufficiency in all patients, a residual pressure gradient in the RVOT in seven and a residual ventricular septal defect in two patients. Surgery was indicated in eight patients because of progressive distension of the aneurysm. Reconstruction of the RVOT was accomplished by resection of the aneurysm and insertion of a woven Dacron patch in five patients, primary suture of the pulmonary artery in two and implantation of a woven Dacron conduit containing a Björk-Shiley valve in one patient. No early or late death occured. Although aneurysms of the RVOT with pericardial patches represent a rare complication after total correction of tetralogy of Fallot, we recommend primary reconstruction of the RVOT with a woven Dacron patch.

Generation of glycans depleted decellularized porcine pericardium, using digestive enzymatic supplements and enzymatic mixtures for food industry

“…and N-acetylneuraminic acid (Neu5Ac); nevertheless, its affinity to Neu5Gc is much lower than that to Neu5Ac. 59,60 WGA has also been reported for staining sugar moieties on glycolipids, 61 such as the monosialotetrahexosylganglioside (GM1), 62 and the glycolipids IV 3 NeuAc-nLcOse 4 Cer and IV 6 NeuAc-nLcOse 4 Cer. 63 Also RCA I and PNA have been reported for binding to GM1.…”

“…Pericardium of autologous, homologous, and xenogeneic origin has been used extensively in the clinic for cardiovascular tissue reconstruction. In particular, glutaraldehyde (GA)‐fixed xenogeneic pericardium has been largely employed due to its substantial availability, for various applications such as pericardial closure in the prevention of cardiac herniation, 1 ventricular outflow tract reconstruction in treatments of congenital and acquired heart defects, 2,3 carotid endarterectomy in vascular surgery, 4 and, finally, valvular reconstruction 5,6 . Despite GA‐treated xenogeneic pericardium has shown a better performance over other reconstruction strategies, such as synthetic grafts, its use has often been associated with inflammation, calcification, aneurysmal dilatation, and lack of in vivo regeneration, and finally, leading to reoperation 2,7‐9 .…”